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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
CT
1601
Chicago Trust
Illinois
$889K -$1.4M -4,824 -60%
CL
1602
COWA LLC
Oklahoma
$889K -$4.35K -15 -0.5%
WAM
1603
Wolverine Asset Management
Illinois
$886K -$902K -3,110 -50%
GWS
1604
Greykasell Wealth Strategies
California
$886K +$49.6K +171 +6%
HIMS
1605
Hager Investment Management Services
New Hampshire
$882K -$562K -1,938 -38%
MPIA
1606
Milestones Private Investment Advisors
New York
$882K
CPA
1607
Court Place Advisors
Maryland
$881K
LAM
1608
Lewis Asset Management
California
$877K -$8.12K -28 -0.9%
GSB
1609
Greenfield Savings Bank
Massachusetts
$877K -$36.5K -126 -4%
MLA
1610
MB, Levis & Associates
Pennsylvania
$876K -$201K -694 -18%
MC
1611
Mathes Company
New York
$876K -$17.4K -60 -2%
AFA
1612
Antonelli Financial Advisors
Michigan
$875K -$14.5K -50 -2%
UCB
1613
United Community Bank
South Carolina
$874K -$1.11M -3,842 -55%
PIA
1614
Perennial Investment Advisors
California
$872K +$32.8K +113 +4%
GCA
1615
Gradient Capital Advisors
California
$871K +$8.7K +30 +1%
RMDI
1616
R.M. Davis Inc
Maine
$868K -$30.7K -106 -3%
CWP
1617
CFM Wealth Partners
Texas
$867K -$3.48K -12 -0.4%
SAW
1618
Signal Advisors Wealth
Michigan
$867K -$936K -3,226 -51%
C
1619
Certuity
Florida
$867K +$118K +406 +15%
MAM
1620
MWA Asset Management
Massachusetts
$866K +$2.03K +7 +0.2%
PWM
1621
Paulson Wealth Management
Illinois
$863K +$22.3K +77 +3%
PEAK6
1622
PEAK6
Illinois
$862K -$3.29M -11,329 -79%
BF
1623
bLong Financial
Tennessee
$861K
NPA
1624
Nichols & Pratt Advisers
Massachusetts
$860K
PI
1625
Pettee Investors
Connecticut
$858K -$326K -1,125 -27%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.