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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
LJAC
1476
L.J. Altfest & Co
New York
$1.09M
HCP
1477
Holt Capital Partners
Texas
$1.09M
BA
1478
Birinyi Associates
Connecticut
$1.08M
TPA
1479
Trivium Point Advisory
Connecticut
$1.08M +$64.7K +223 +6%
LF
1480
Lee Financial
Texas
$1.08M +$48.4K +167 +5%
BFG
1481
Berger Financial Group
Minnesota
$1.08M +$4.93K +17 +0.4%
GP
1482
Greenline Partners
New York
$1.08M -$324K -1,116 -23%
APG
1483
Abacus Planning Group
South Carolina
$1.08M -$13.1K -45 -1%
VA
1484
VestGen Advisors
Illinois
$1.08M +$191K +657 +21%
HPM
1485
Hudson Portfolio Management
New York
$1.07M -$14.5K -50 -1%
CCIA
1486
Campbell & Co Investment Adviser
Maryland
$1.07M +$1.1M +3,785 New
FCM
1487
Fourpath Capital Management
Oklahoma
$1.07M -$16K -55 -1%
NI
1488
Natural Investments
California
$1.07M +$9.28K +32 +0.9%
CT
1489
Colonial Trust
South Carolina
$1.06M -$4.93K -17 -0.5%
IRP
1490
Investment Research Partners
Pennsylvania
$1.06M +$1.05M +3,633 New
GIA
1491
Guyasuta Investment Advisors
Pennsylvania
$1.06M +$1.74K +6 +0.2%
VAG
1492
VisionPoint Advisory Group
Texas
$1.06M +$71.6K +247 +7%
HAM
1493
Harmony Asset Management
Arizona
$1.05M
LOPW
1494
Live Oak Private Wealth
North Carolina
$1.05M -$2.9K -10 -0.3%
CI
1495
Conning Inc
Connecticut
$1.05M -$69.9K -241 -6%
MF
1496
Manchester Financial
California
$1.05M -$1.74K -6 -0.2%
TIA
1497
Trust Investment Advisors
Indiana
$1.05M +$34.2K +118 +3%
DFC
1498
DB Fitzpatrick & Co
Idaho
$1.05M -$25.5K -88 -2%
BDFN
1499
Bond & Devick Financial Network
Minnesota
$1.05M +$580 +2 +0.1%
PCM
1500
Princeton Capital Management
New Jersey
$1.04M -$193K -664 -15%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.