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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
Man Group
126
Man Group
United Kingdom
$81.1M +$16.8M +58,016 +25%
SG Americas Securities
127
SG Americas Securities
New York
$80M +$13.5M +46,504 +20%
State of Wisconsin Investment Board
128
State of Wisconsin Investment Board
Wisconsin
$79.8M -$1.24M -4,273 -1%
Baird Financial Group
129
Baird Financial Group
Wisconsin
$79.5M -$786K -2,709 -1%
Royal London Asset Management
130
Royal London Asset Management
United Kingdom
$79.5M -$1.92M -6,604 -2%
Chevy Chase Trust
131
Chevy Chase Trust
Maryland
$79.2M -$2.72M -9,383 -3%
Mitsubishi UFJ Trust & Banking
132
Mitsubishi UFJ Trust & Banking
Japan
$77.9M -$265K -914 -0.3%
SLAM
133
Swiss Life Asset Management
$76.6M +$1.76M +6,082 +2%
Zurich Cantonal Bank
134
Zurich Cantonal Bank
Switzerland
$76.3M -$35.4M -122,181 -31%
Allianz Asset Management
135
Allianz Asset Management
Germany
$75.7M -$17.8M -61,503 -19%
Russell Investments Group
136
Russell Investments Group
United Kingdom
$75M +$7.09M +24,446 +10%
JSSH
137
J. Safra Sarasin Holding
$69.7M +$1.98M +6,833 +3%
Osaic Holdings
138
Osaic Holdings
Arizona
$69.7M +$23.8M +82,017 +50%
GC
139
Guggenheim Capital
Illinois
$69.5M +$2.67M +9,223 +4%
P
140
&Partners
Tennessee
$69M +$588K +2,027 +0.8%
DADC
141
D.A. Davidson & Co
Montana
$68.6M +$1.8M +6,222 +3%
Treasurer of the State of North Carolina
142
Treasurer of the State of North Carolina
North Carolina
$68.2M -$2.73M -9,421 -4%
QCM
143
Quantinno Capital Management
New York
$68.2M +$13.3M +45,871 +23%
Adage Capital Partners
144
Adage Capital Partners
Massachusetts
$67.1M +$14.2M +48,828 +26%
Daiwa Securities Group
145
Daiwa Securities Group
Japan
$66.5M +$1.69M +5,827 +3%
CB
146
Commerce Bank
Missouri
$66.4M -$3.78M -13,030 -5%
NIM
147
NEOS Investment Management
Connecticut
$64.7M +$21.7M +74,877 +48%
Focus Partners Wealth
148
Focus Partners Wealth
Massachusetts
$64.3M +$2.56M +8,839 +4%
Ensign Peak Advisors
149
Ensign Peak Advisors
Utah
$63.9M -$24.6M -84,766 -27%
Toronto Dominion Bank
150
Toronto Dominion Bank
Ontario, Canada
$63.4M -$10.6M -36,430 -14%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.