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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
KOC
1451
Koss-Olinger Consulting
Florida
$1.17M -$7.93K -28 -0.7%
TC
1452
TAGStone Capital
North Carolina
$1.17M +$93.8K +331 +9%
TCPW
1453
Twin City Private Wealth
North Carolina
$1.17M +$6.23K +22 +0.5%
MMM
1454
Mendel Money Management
Illinois
$1.17M -$64.9K -229 -5%
EFS
1455
Econ Financial Services
Pennsylvania
$1.17M +$1.18M +4,177 New
PI
1456
Pettee Investors
Connecticut
$1.16M -$88.7K -313 -7%
SCP
1457
Stamos Capital Partners
California
$1.16M +$127K +449 +12%
CAM
1458
Carret Asset Management
New York
$1.15M -$4.53K -16 -0.4%
WWM
1459
Western Wealth Management
Colorado
$1.15M +$86.7K +306 +8%
NHT
1460
New Hampshire Trust
New Hampshire
$1.15M +$21.2K +75 +2%
HIG
1461
Heritage Investment Group
Florida
$1.15M
HWP
1462
Highline Wealth Partners
California
$1.15M +$7.08K +25 +0.6%
CAC
1463
Core Alternative Capital
Georgia
$1.15M -$286K -1,008 -20%
Two Sigma Advisers
1464
Two Sigma Advisers
New York
$1.14M -$283M -997,300 -100%
FWM
1465
Forefront Wealth Management
Pennsylvania
$1.14M -$8.5K -30 -0.7%
JIP
1466
Jaffetilchin Investment Partners
Florida
$1.14M -$358K -1,262 -24%
AIA
1467
Affinity Investment Advisors
California
$1.14M -$78.5K -277 -6%
JIR
1468
James Investment Research
Ohio
$1.14M -$283 -1 -0%
MSFS
1469
Main Street Financial Solutions
Pennsylvania
$1.14M +$118K +416 +11%
MIM
1470
Morningstar Investment Management
Illinois
$1.14M +$1.16M +4,084 New
PFSC
1471
Peoples Financial Services Corp
Pennsylvania
$1.14M -$218K -771 -16%
PCA
1472
Pallas Capital Advisors
Massachusetts
$1.14M -$152K -535 -12%
PFBT
1473
Parkside Financial Bank & Trust
Missouri
$1.13M +$60.6K +214 +6%
MMHP
1474
Murphy Middleton Hinkle & Parker
Georgia
$1.13M
RPC
1475
Rossmore Private Capital
Connecticut
$1.13M +$28.9K +102 +3%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.