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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
SMA
1351
Sage Mountain Advisors
Georgia
$1.39M -$64.4K -222 -4%
PDL
1352
Portfolio Design Labs
California
$1.39M +$1.43M +4,922 New
DA
1353
Doliver Advisors
Texas
$1.39M +$5.22K +18 +0.4%
FFN
1354
Focus Financial Network
Minnesota
$1.38M +$32.5K +112 +2%
HCM
1355
Hodges Capital Management
Texas
$1.37M -$2M -6,887 -59%
MA
1356
MJP Associates
Connecticut
$1.37M +$23.8K +82 +2%
SGI
1357
Summit Global Investments
Utah
$1.36M -$57.7K -199 -4%
CYG
1358
Clean Yield Group
Vermont
$1.36M -$93.7K -323 -6%
MC
1359
Martin & Co
Tennessee
$1.36M
RIA
1360
Regal Investment Advisors
Michigan
$1.35M +$51.9K +179 +4%
PPA
1361
Painted Porch Advisors
California
$1.34M -$7.25K -25 -0.5%
SCM
1362
SCS Capital Management
Massachusetts
$1.34M -$195K -671 -12%
KTC
1363
Kentucky Trust Company
Kentucky
$1.34M
BHCM
1364
Brevan Howard Capital Management
Jersey
$1.34M -$4.05M -13,968 -75%
MWM
1365
Modern Wealth Management
Kansas
$1.34M -$62.4K -215 -4%
TCCM
1366
Timber Creek Capital Management
Massachusetts
$1.33M
AA
1367
Argent Advisors
Louisiana
$1.33M -$9.86K -34 -0.7%
PPWP
1368
Premier Path Wealth Partners
New Jersey
$1.33M -$5.51K -19 -0.4%
GXJ
1369
Global X Japan
Japan
$1.32M +$1.34M +4,610 +5,554%
V
1370
VeraBank
Texas
$1.32M +$2.61K +9 +0.2%
CPWA
1371
Cerro Pacific Wealth Advisors
California
$1.32M -$195K -674 -13%
VH
1372
Visionary Horizons
Tennessee
$1.32M -$22.9K -79 -2%
QI
1373
Qtron Investments
Massachusetts
$1.32M -$386K -1,330 -22%
RBA
1374
Richard Bernstein Advisors
New York
$1.32M -$2.51M -8,655 -65%
AFT
1375
Alpha Family Trust
California
$1.32M

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.