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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
NRI
1276
NFP Retirement Inc
California
$1.56M -$1.32M -4,564 -45%
CB
1277
Cadence Bank
Mississippi
$1.55M +$42.1K +145 +3%
FMTC
1278
Farmers & Merchants Trust Company
California
$1.55M -$89K -307 -5%
PAM
1279
Parvin Asset Management
South Dakota
$1.54M -$35.1K -121 -2%
ET
1280
Equitable Trust
Tennessee
$1.54M +$140K +482 +10%
LIM
1281
Loudon Investment Management
New Hampshire
$1.54M -$626K -2,157 -28%
MCM
1282
Mainstay Capital Management
Michigan
$1.54M -$1.41M -4,865 -47%
TCMP
1283
Thrive Capital Management (Pennsylvania)
Pennsylvania
$1.54M -$396K -1,367 -20%
PPA
1284
Pacific Point Advisors
California
$1.53M +$26.1K +90 +2%
GIP
1285
Granite Investment Partners
California
$1.53M
CGFA
1286
Colton Groome Financial Advisors
North Carolina
$1.53M +$58K +200 +4%
RC
1287
Rexford Capital
Texas
$1.53M +$8.12K +28 +0.5%
PSP
1288
Pacific Sage Partners
Washington
$1.52M +$38.6K +133 +3%
PAMG
1289
Patton Albertson Miller Group
Tennessee
$1.52M +$396K +1,364 +34%
AP
1290
Appleton Partners
Massachusetts
$1.52M -$230K -794 -13%
HCMG
1291
Howard Capital Management Group
California
$1.52M +$11.6K +40 +0.7%
OP
1292
ORG Partners
Indiana
$1.51M +$4.64K +16 +0.3%
SIA
1293
Strategic Investment Advisors
Michigan
$1.51M -$237K -817 -13%
IAS
1294
Investment Advisory Services
Texas
$1.51M -$76.6K -264 -5%
SJIM
1295
St. Johns Investment Management
Florida
$1.51M -$10.7K -37 -0.7%
DF
1296
Donoghue Forlines
Massachusetts
$1.51M +$84.1K +290 +6%
KCM
1297
Kennedy Capital Management
Missouri
$1.51M +$726K +2,503 +88%
OFS
1298
OMC Financial Services
New York
$1.51M +$49.3K +170 +3%
PWM
1299
Palacios Wealth Management
Florida
$1.5M +$37.7K +130 +2%
GSEP
1300
Golden State Equity Partners
California
$1.5M -$166K -571 -10%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.