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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
TF
1226
Trek Financial
Arizona
$1.7M +$383K +1,322 +28%
CCA
1227
Checchi Capital Advisers
California
$1.7M -$209K -719 -11%
EWA
1228
Encompass Wealth Advisors
Oregon
$1.7M
GA
1229
Greenspring Advisors
Maryland
$1.69M +$1.74M +6,000 New
MGWM
1230
Marks Group Wealth Management
Minnesota
$1.69M +$45K +155 +3%
CC
1231
Centiva Capital
New York
$1.69M +$1.74M +5,998 New
MA
1232
MKT Advisors
California
$1.69M -$31.3K -108 -2%
RCAG
1233
Rehmann Capital Advisory Group
Michigan
$1.69M -$851K -2,934 -33%
BFC
1234
Blue Fin Capital
Rhode Island
$1.68M -$12.8K -44 -0.7%
SAG
1235
SageView Advisory Group
California
$1.68M -$729K -2,512 -30%
FBB
1236
Fulton Breakefield Broenniman
Maryland
$1.67M +$25.5K +88 +2%
FAB
1237
First American Bank
Illinois
$1.67M
PWA
1238
Providence Wealth Advisors
Illinois
$1.67M -$13.1K -45 -0.8%
SPC
1239
Spirepoint Private Client
Florida
$1.67M +$137K +471 +9%
NSEDCP
1240
NJ State Employees Deferred Compensation Plan
New Jersey
$1.66M -$325K -1,120 -16%
FFA
1241
Fairfield Financial Advisors
Massachusetts
$1.66M -$459K -1,584 -21%
HI
1242
Hudock Inc
Pennsylvania
$1.65M +$11.3K +39 +0.7%
BIG
1243
Brooklyn Investment Group
New York
$1.65M -$17.1K -59 -1%
BWG
1244
Boomfish Wealth Group
Georgia
$1.65M +$36.5K +126 +2%
ACM
1245
Aljian Capital Management
Nevada
$1.65M -$8.99K -31 -0.5%
KAS
1246
KPP Advisory Services
Kentucky
$1.65M -$17.7K -61 -1%
GPA
1247
Garrison Point Advisors
California
$1.64M -$31.3K -108 -2%
BSB
1248
Bangor Savings Bank
Maine
$1.64M +$20.3K +70 +1%
CWM
1249
Calamos Wealth Management
Illinois
$1.64M +$972K +3,351 +136%
LJHT
1250
Laurie J. Hall Trustee
$1.64M

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.