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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
SEIA
1201
Signature Estate & Investment Advisors
California
$1.77M +$12.8K +44 +0.7%
FAM
1202
Formidable Asset Management
Ohio
$1.76M -$425K -1,467 -19%
MWM
1203
Massachusetts Wealth Management
Massachusetts
$1.76M -$78K -269 -4%
TWP
1204
Tempus Wealth Planning
California
$1.76M +$39.7K +137 +2%
MYIA
1205
Mount Yale Investment Advisors
Colorado
$1.76M +$1.56M +5,370 +627%
AP
1206
Atwood & Palmer
Missouri
$1.76M
MPIA
1207
Mountain Pacific Investment Advisers
Idaho
$1.76M -$43.5K -150 -2%
WDC
1208
Woodward Diversified Capital
California
$1.75M +$2.9K +10 +0.2%
EWM
1209
EPG Wealth Management
Georgia
$1.75M +$173K +595 +11%
SIAG
1210
Signet Investment Advisory Group
Rhode Island
$1.75M +$22K +76 +1%
WCBA
1211
Weaver C. Barksdale & Associates
Tennessee
$1.75M -$113K -389 -6%
NWMG
1212
Nicholson Wealth Management Group
South Carolina
$1.75M +$78.9K +272 +5%
SFM
1213
Signet Financial Management
New Jersey
$1.74M -$96.6K -333 -5%
TAM
1214
Trust Asset Management
Texas
$1.74M
AFCM
1215
Applied Finance Capital Management
Puerto Rico
$1.74M -$54.2K -187 -3%
MCM
1216
Morton Capital Management
California
$1.74M -$65.5K -226 -4%
AWE
1217
Avidian Wealth Enterprises
Texas
$1.73M +$94.3K +325 +6%
MPWT
1218
MassMutual Private Wealth & Trust
Connecticut
$1.73M -$48.7K -168 -3%
AA
1219
Armis Advisers
Georgia
$1.72M +$230K +793 +16%
CG
1220
Curat Global
New Hampshire
$1.72M
MIA
1221
MMBG Investment Advisors
Florida
$1.72M
CPIG
1222
Chicago Partners Investment Group
Illinois
$1.72M +$15.7K +54 +0.9%
TCWA
1223
Turtle Creek Wealth Advisors
Texas
$1.71M +$116K +401 +7%
OWP
1224
ORG Wealth Partners
Texas
$1.71M +$64.4K +222 +4%
MCM
1225
Mengis Capital Management
Oregon
$1.71M

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.