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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
Principal Financial Group
76
Principal Financial Group
Iowa
$168M -$6.16M -21,747 -3%
Canada Pension Plan Investment Board
77
Canada Pension Plan Investment Board
Ontario, Canada
$158M +$14.2M +50,211 +10%
Mirae Asset Global Investments
78
Mirae Asset Global Investments
South Korea
$152M +$15.9M +56,183 +12%
First Trust Advisors
79
First Trust Advisors
Illinois
$149M -$6.05M -21,347 -4%
Rockefeller Capital Management
80
Rockefeller Capital Management
New York
$149M +$9.79M +34,559 +7%
Thrivent Financial for Lutherans
81
Thrivent Financial for Lutherans
Minnesota
$148M +$18.6M +65,560 +14%
Corient Private Wealth
82
Corient Private Wealth
Florida
$145M -$3.25M -11,477 -2%
Assenagon Asset Management
83
Assenagon Asset Management
Luxembourg
$145M +$138M +486,299 +1,505%
State Board of Administration of Florida Retirement System
84
State Board of Administration of Florida Retirement System
Florida
$144M +$1.42M +5,010 +1%
Luther King Capital Management (LKCM)
85
Luther King Capital Management (LKCM)
Texas
$142M -$1.86M -6,577 -1%
CS
86
Candriam SCA
Luxembourg
$141M -$137K -483 -0.1%
PAM
87
Panagora Asset Management
Massachusetts
$137M +$109M +385,517 +367%
MMC
88
Mizuho Markets Cayman
Cayman Islands
$136M +$138M +485,647 New
DB
89
Danske Bank
Denmark
$135M +$13.6M +47,957 +11%
VOYA Investment Management
90
VOYA Investment Management
Georgia
$132M -$29M -102,298 -18%
Universal-Beteiligungs- und Servicegesellschaft
91
Universal-Beteiligungs- und Servicegesellschaft
Germany
$130M -$36.6M -129,101 -22%
CAPTRUST Financial Advisors
92
CAPTRUST Financial Advisors
North Carolina
$128M +$1.1M +3,873 +0.9%
New York State Teachers Retirement System (NYSTRS)
93
New York State Teachers Retirement System (NYSTRS)
New York
$125M +$2.38M +8,392 +2%
Robeco Institutional Asset Management
94
Robeco Institutional Asset Management
Netherlands
$124M -$5.31M -18,753 -4%
Mirae Asset Global ETFs Holdings
95
Mirae Asset Global ETFs Holdings
Hong Kong
$124M -$10.7M -37,607 -8%
MGP
96
M&G plc
United Kingdom
$122M +$5.58M +19,708 +5%
Wealth Enhancement Advisory Services
97
Wealth Enhancement Advisory Services
Minnesota
$119M +$3.97M +14,017 +4%
Cerity Partners
98
Cerity Partners
New York
$118M +$4.81M +16,972 +4%
Commonwealth Equity Services
99
Commonwealth Equity Services
Massachusetts
$115M -$1.31M -4,622 -1%
Fisher Asset Management
100
Fisher Asset Management
Washington
$114M -$7.93M -28,003 -6%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.