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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,123 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,123 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,123
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
HA
851
Hofer & Associates
California
$3.62M +$1.64M +5,658 +79%
ECM
852
Everence Capital Management
Indiana
$3.62M
GWM
853
GSB Wealth Management
Connecticut
$3.61M -$38.6K -133 -1%
WC
854
Woodstock Corp
Massachusetts
$3.59M -$65.5K -226 -2%
AW
855
Alteri Wealth
California
$3.58M +$296K +1,021 +9%
RA
856
RFG Advisory
Alabama
$3.57M +$134K +462 +4%
GWMR
857
GC Wealth Management RIA
Massachusetts
$3.56M +$1.26M +4,340 +52%
IAN
858
Integrated Advisors Network
Texas
$3.56M +$193K +667 +6%
MYAM
859
Meiji Yasuda Asset Management
Japan
$3.55M -$111K -383 -3%
IWM
860
IHT Wealth Management
Illinois
$3.54M +$26.4K +91 +0.7%
EH
861
Equitable Holdings
New York
$3.53M +$103K +355 +3%
SC
862
Slow Capital
California
$3.52M +$77.1K +266 +2%
WAP
863
Wealthcare Advisory Partners
Pennsylvania
$3.52M +$290 +1 +0%
Kayne Anderson Rudnick Investment Management
864
Kayne Anderson Rudnick Investment Management
California
$3.52M +$127K +439 +4%
FBT
865
First Bank & Trust
South Dakota
$3.5M +$335K +1,155 +10%
GAM
866
Groupama Asset Management
France
$3.49M -$406K -1,401 -10%
GLR
867
Great Lakes Retirement
Ohio
$3.46M +$258K +891 +8%
BCA
868
Bay Colony Advisors
Massachusetts
$3.45M +$110K +378 +3%
EG
869
Ellerson Group
Maryland
$3.43M +$120K +414 +4%
OPCM
870
Osborne Partners Capital Management
California
$3.42M
FFA
871
Fragasso Financial Advisors
Pennsylvania
$3.41M -$1.75M -6,049 -35%
OAM
872
Ostrum Asset Management
France
$3.4M -$101K -348 -3%
CC
873
Chicago Capital
Illinois
$3.4M -$253K -872 -7%
Koshinski Asset Management
874
Koshinski Asset Management
Illinois
$3.39M -$82.4K -284 -2%
CIA
875
Cohen Investment Advisors
New Hampshire
$3.39M +$188K +648 +6%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,123 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.