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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
QCG
776
Quadrant Capital Group
Ohio
$4.18M -$89.6K -309 -2%
TBA
777
Tower Bridge Advisors
Pennsylvania
$4.17M -$580 -2 -0%
TCM
778
Twin Capital Management
Pennsylvania
$4.17M -$1.61M -5,541 -27%
VCM
779
Voleon Capital Management
California
$4.15M +$548K +1,891 +15%
BTW
780
Boston Trust Walden
Massachusetts
$4.14M -$5.59M -19,260 -57%
BAAM
781
Baker Avenue Asset Management
California
$4.14M -$15.7K -54 -0.4%
XSC
782
X-Square Capital
Puerto Rico
$4.13M +$50.8K +175 +1%
RHIG
783
R.H. Investment Group
Arizona
$4.13M
BL
784
BFSG LLC
California
$4.12M +$251K +864 +6%
EP
785
Edgestream Partners
New Jersey
$4.11M -$3.49M -12,022 -45%
GCA
786
Greenwood Capital Associates
South Carolina
$4.1M -$12.8K -44 -0.3%
WFMPM
787
Woodley Farra Manion Portfolio Management
Indiana
$4.1M +$2.9K +10 +0.1%
MSA
788
MUFG Securities Americas
New York
$4.1M +$754K +2,601 +22%
SPC
789
Sigma Planning Corp
Michigan
$4.09M -$352K -1,215 -8%
CIA
790
Choate Investment Advisors
Massachusetts
$4.09M -$506K -1,745 -11%
JGCM
791
Joseph Group Capital Management
Ohio
$4.08M +$608K +2,098 +17%
RWP
792
Revolve Wealth Partners
New Jersey
$4.08M -$193K -666 -4%
SL
793
Sentry LLC
Tennessee
$4.07M -$109K -375 -3%
BFS
794
Bradley Foster & Sargent
Connecticut
$4.07M -$387K -1,336 -8%
CBA
795
Coastal Bridge Advisors
Connecticut
$4.04M +$126K +433 +3%
SW
796
StrongBox Wealth
Missouri
$4.03M +$540K +1,863 +15%
MWM
797
Meridian Wealth Management
Kentucky
$4.03M -$121K -416 -3%
MA
798
Mutual Advisors
Nebraska
$4.03M -$677K -2,333 -14%
KB
799
Kimelman & Baird
New York
$4.02M -$160K -550 -4%
KRSITF
800
Kentucky Retirement Systems Insurance Trust Fund
Kentucky
$3.99M -$126K -434 -3%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.