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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
T. Rowe Price Associates
51
T. Rowe Price Associates
Maryland
$298M -$25.2M -86,945 -8%
Mariner
52
Mariner
Kansas
$297M +$4.65M +16,031 +2%
RhumbLine Advisers
53
RhumbLine Advisers
Massachusetts
$270M -$1.94M -6,685 -0.7%
Manulife (Manufacturers Life Insurance)
54
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$263M -$21.4M -73,826 -7%
California State Teachers Retirement System (CalSTRS)
55
California State Teachers Retirement System (CalSTRS)
California
$243M +$1.88M +6,471 +0.8%
SCM
56
Smead Capital Management
Arizona
$242M -$19M -65,584 -7%
CWP
57
Capital Wealth Planning
Florida
$233M -$137M -472,530 -36%
Citigroup
58
Citigroup
New York
$228M -$29.5M -101,787 -11%
ProShare Advisors
59
ProShare Advisors
Maryland
$223M -$46.1M -158,994 -17%
HighTower Advisors
60
HighTower Advisors
Illinois
$223M +$10.7M +36,897 +5%
Fisher Asset Management
61
Fisher Asset Management
Washington
$222M +$109M +375,463 +92%
Canada Pension Plan Investment Board
62
Canada Pension Plan Investment Board
Ontario, Canada
$220M +$62.2M +214,471 +38%
BNP Paribas Financial Markets
63
BNP Paribas Financial Markets
France
$209M -$53.3M -183,846 -20%
Boston Partners
64
Boston Partners
Massachusetts
$204M -$7.15M -24,652 -3%
DekaBank Deutsche Girozentrale
65
DekaBank Deutsche Girozentrale
Germany
$195M
US Bancorp
66
US Bancorp
Minnesota
$194M -$6.44M -22,217 -3%
Prudential Financial
67
Prudential Financial
New Jersey
$191M -$19.7M -67,785 -9%
Victory Capital Management
68
Victory Capital Management
Texas
$187M -$103M -354,439 -35%
SP
69
Sarasin & Partners
United Kingdom
$181M +$13.9M +47,873 +8%
Pictet Asset Management
70
Pictet Asset Management
Switzerland
$179M -$72M -248,094 -28%
New York State Common Retirement Fund
71
New York State Common Retirement Fund
New York
$176M -$11.5M -39,789 -6%
AllianceBernstein
72
AllianceBernstein
Tennessee
$168M -$129M -444,604 -43%
Principal Financial Group
73
Principal Financial Group
Iowa
$167M -$2.2M -7,582 -1%
Mirae Asset Global Investments
74
Mirae Asset Global Investments
South Korea
$167M +$13.9M +47,958 +9%
Aberdeen Group
75
Aberdeen Group
United Kingdom
$167M -$22.1M -76,076 -11%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.