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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
Victory Capital Management
51
Victory Capital Management
Texas
$284M +$18.4M +65,060 +7%
PNC Financial Services Group
52
PNC Financial Services Group
Pennsylvania
$282M -$3.99M -14,067 -1%
Bank of Montreal
53
Bank of Montreal
Ontario, Canada
$282M -$33.5M -118,300 -10%
Manulife (Manufacturers Life Insurance)
54
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$281M -$17M -60,112 -6%
LPL Financial
55
LPL Financial
California
$279M +$27.5M +96,983 +11%
RhumbLine Advisers
56
RhumbLine Advisers
Massachusetts
$269M -$4.19M -14,804 -2%
ProShare Advisors
57
ProShare Advisors
Maryland
$265M +$9.9M +34,959 +4%
BNP Paribas Financial Markets
58
BNP Paribas Financial Markets
France
$258M -$101M -357,450 -28%
SCM
59
Smead Capital Management
Arizona
$258M -$34.9M -123,046 -12%
Citigroup
60
Citigroup
New York
$254M +$7.36M +25,984 +3%
Pictet Asset Management
61
Pictet Asset Management
Switzerland
$248M -$5.87M -20,726 -2%
California State Teachers Retirement System (CalSTRS)
62
California State Teachers Retirement System (CalSTRS)
California
$239M +$3.81M +13,432 +2%
VanEck Associates
63
VanEck Associates
New York
$221M -$45.9M -162,164 -17%
Swedbank
64
Swedbank
Sweden
$215M +$27M +95,470 +14%
HighTower Advisors
65
HighTower Advisors
Illinois
$210M +$6.94M +24,505 +3%
Boston Partners
66
Boston Partners
Massachusetts
$209M -$15.6M -55,019 -7%
Prudential Financial
67
Prudential Financial
New Jersey
$208M +$6.11M +21,561 +3%
DekaBank Deutsche Girozentrale
68
DekaBank Deutsche Girozentrale
Germany
$198M -$15.9M -56,296 -7%
US Bancorp
69
US Bancorp
Minnesota
$198M -$6.06M -21,405 -3%
Aberdeen Group
70
Aberdeen Group
United Kingdom
$189M -$23.8M -83,945 -11%
New York State Common Retirement Fund
71
New York State Common Retirement Fund
New York
$186M -$1.76M -6,221 -0.9%
Truist Financial
72
Truist Financial
North Carolina
$176M -$4.78M -16,871 -3%
D.E. Shaw & Co
73
D.E. Shaw & Co
New York
$175M -$180M -635,803 -50%
SP
74
Sarasin & Partners
United Kingdom
$171M +$15.5M +54,580 +10%
Jennison Associates
75
Jennison Associates
New York
$169M +$122M +431,036 +248%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.