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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
State Farm Mutual Automobile Insurance
26
State Farm Mutual Automobile Insurance
Illinois
$766M
Barclays
27
Barclays
United Kingdom
$761M +$87.8M +302,630 +13%
Janus Henderson Group
28
Janus Henderson Group
United Kingdom
$746M -$69.7M -240,353 -8%
Franklin Resources
29
Franklin Resources
California
$746M -$102M -352,045 -12%
Deutsche Bank
30
Deutsche Bank
Germany
$745M +$31.9M +110,020 +4%
Amundi
31
Amundi
France
$708M +$30.4M +104,920 +5%
California Public Employees Retirement System
32
California Public Employees Retirement System
California
$590M -$58.9M -202,929 -9%
Federated Hermes
33
Federated Hermes
Pennsylvania
$589M -$24.4M -84,270 -4%
N
34
Nuveen
North Carolina
$579M -$19.3M -66,697 -3%
Ameriprise
35
Ameriprise
Minnesota
$564M -$135M -467,013 -19%
Raymond James Financial
36
Raymond James Financial
Florida
$493M +$6.06M +20,888 +1%
Sumitomo Mitsui Trust Group
37
Sumitomo Mitsui Trust Group
Japan
$467M -$13.3M -45,938 -3%
Pacer Advisors
38
Pacer Advisors
Pennsylvania
$455M -$30.5M -105,180 -6%
Swiss National Bank
39
Swiss National Bank
Switzerland
$437M -$22.5M -77,600 -5%
Stifel Financial
40
Stifel Financial
Missouri
$435M +$7.36M +25,384 +2%
BGC
41
Beutel, Goodman & Co
Ontario, Canada
$408M +$2.99M +10,308 +0.7%
HSBC Holdings
42
HSBC Holdings
United Kingdom
$402M +$90.2M +311,092 +28%
VanEck Associates
43
VanEck Associates
New York
$383M +$165M +567,400 +72%
Envestnet Asset Management
44
Envestnet Asset Management
Illinois
$367M -$59M -203,567 -14%
Mitsubishi UFJ Asset Management
45
Mitsubishi UFJ Asset Management
Japan
$349M +$12.8M +44,044 +4%
National Bank of Canada
46
National Bank of Canada
Quebec, Canada
$346M +$251M +866,166 +240%
National Pension Service
47
National Pension Service
South Korea
$334M +$10.9M +37,747 +3%
LPL Financial
48
LPL Financial
California
$322M +$40.9M +141,103 +14%
PNC Financial Services Group
49
PNC Financial Services Group
Pennsylvania
$315M +$30.5M +105,183 +10%
Bank of Montreal
50
Bank of Montreal
Ontario, Canada
$300M +$15.5M +53,566 +5%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.