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Amgen
AMGN

2,927 hedge funds and large institutions have $133B invested in Amgen in 2025 Q1 according to their latest regulatory filings, with 249 funds opening new positions, 1,134 increasing their positions, 1,184 reducing their positions, and 132 closing their positions.

New
Increased
Maintained
Reduced
Closed

100% more funds holding in top 10

Funds holding in top 10: 37 → 74 (+37)

89% more first-time investments, than exits

New positions opened: 249 | Existing positions closed: 132

19% more capital invested

Capital invested by funds: $112B → $133B (+$21.6B)

2% more funds holding

Funds holding: 2,856 → 2,927 (+71)

1.97% more ownership

Funds ownership: 77.85% → 79.82% (+2%)

8% more call options, than puts

Call options by funds: $2.74B | Put options by funds: $2.55B

4% less repeat investments, than reductions

Existing positions increased: 1,134 | Existing positions reduced: 1,184

Holders
2,927
Holders Change
+71
Holders Change %
+2.49%
% of All Funds
39.24%
Holding in Top 10
74
Holding in Top 10 Change
+37
Holding in Top 10 Change %
+100%
% of All Funds
0.99%
New
249
Increased
1,134
Reduced
1,184
Closed
132
Calls
$2.74B
Puts
$2.55B
Net Calls
+$193M
Net Calls Change
+$27.3M

Top Buyers

Rank Fund Capital Flow
1
Capital World Investors
Capital World Investors
California
+$3.01B
2
Capital International Investors
Capital International Investors
California
+$863M
3
Morgan Stanley
Morgan Stanley
New York
+$494M
4
Pacer Advisors
Pacer Advisors
Pennsylvania
+$440M
5
JP Morgan Chase
JP Morgan Chase
New York
+$382M

Top Sellers

Rank Fund Capital Flow
1
Boston Partners
Boston Partners
Massachusetts
-$431M
2
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT)
United Kingdom
-$322M
3
Charles Schwab
Charles Schwab
California
-$295M
4
D.E. Shaw & Co
D.E. Shaw & Co
New York
-$211M
5
Amundi
Amundi
France
-$199M
Name Holding Trade Value Shares
Change 		Change in
Stake
Deutsche Bank
26
Deutsche Bank
Germany
$1.02B +$15.6M +52,734 +2%
Dimensional Fund Advisors
27
Dimensional Fund Advisors
Texas
$941M +$6.74M +22,820 +0.8%
State Farm Mutual Automobile Insurance
28
State Farm Mutual Automobile Insurance
Illinois
$846M – – –
Nordea Investment Management
29
Nordea Investment Management
Sweden
$826M +$87M +294,484 +13%
Barclays
30
Barclays
United Kingdom
$797M +$170M +576,630 +29%
Janus Henderson Group
31
Janus Henderson Group
United Kingdom
$780M -$65.4M -221,414 -8%
California Public Employees Retirement System
32
California Public Employees Retirement System
California
$718M +$30.5M +103,156 +5%
N
33
Nuveen
North Carolina
$689M -$62.7M -212,177 -9%
Ameriprise
34
Ameriprise
Minnesota
$663M +$28.6M +96,851 +5%
T. Rowe Price Associates
35
T. Rowe Price Associates
Maryland
$635M -$179M -605,538 -23%
Federated Hermes
36
Federated Hermes
Pennsylvania
$635M +$197M +665,555 +49%
Amundi
37
Amundi
France
$597M -$199M -675,059 -26%
Raymond James Financial
38
Raymond James Financial
Florida
$522M +$39.7M +134,321 +9%
Sumitomo Mitsui Trust Group
39
Sumitomo Mitsui Trust Group
Japan
$519M +$21.4M +72,545 +5%
Pacer Advisors
40
Pacer Advisors
Pennsylvania
$492M +$440M +1,489,446 +1,687%
Swiss National Bank
41
Swiss National Bank
Switzerland
$472M -$561K -1,900 -0.1%
Stifel Financial
42
Stifel Financial
Missouri
$452M +$14.3M +48,472 +3%
Envestnet Asset Management
43
Envestnet Asset Management
Illinois
$442M +$45M +152,514 +12%
BGC
44
Beutel, Goodman & Co
Ontario, Canada
$436M +$37.5M +126,854 +10%
BNP Paribas Financial Markets
45
BNP Paribas Financial Markets
France
$400M +$113M +380,991 +42%
D.E. Shaw & Co
46
D.E. Shaw & Co
New York
$393M -$211M -713,329 -36%
HSBC Holdings
47
HSBC Holdings
United Kingdom
$383M -$44.5M -150,696 -11%
National Pension Service
48
National Pension Service
South Korea
$363M +$20.7M +70,126 +6%
Bank of Montreal
49
Bank of Montreal
Ontario, Canada
$351M -$64M -216,606 -16%
Mitsubishi UFJ Asset Management
50
Mitsubishi UFJ Asset Management
Japan
$348M +$31.5M +106,665 +11%
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AMGN Hedge Fund Activity: Q1 2025 in Review

2,927 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q1 2025, worth a combined $133B — up 19% from $112B a quarter earlier.

Buyers outnumbered sellers: 249 funds opened new AMGN positions and 132 closed out — a net gain of 117 holders — while 1,134 added to existing stakes and 1,184 trimmed.

The largest buyer was Capital World Investors, adding an estimated $3.01B. The largest seller was Boston Partners, cutting an estimated $431M.

  • 2,927 institutional investors held Amgen (AMGN) as of Q1 2025, up from 2,856 in Q4 2024.
  • Funds reported $133B of Amgen stock for Q1 2025, up 19% quarter-over-quarter.
  • 249 funds opened new Amgen positions in Q1 2025 and 132 closed out, a net change of +117 holders.
  • The largest Amgen buyer in Q1 2025 was Capital World Investors, an estimated $3.01B added.
  • The largest Amgen seller in Q1 2025 was Boston Partners, an estimated $431M sold.

Based on aggregated 13F filings for Q1 2025.