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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
MSU
451
Mizuho Securities USA
New York
$10.4M -$1.66M -5,860 -14%
Canada Life
452
Canada Life
Manitoba, Canada
$10.4M -$2.3M -8,128 -18%
CTC
453
Central Trust Company
Missouri
$10.3M -$176K -620 -2%
CA
454
CapWealth Advisors
Tennessee
$10.3M +$495K +1,748 +5%
TI
455
Tidal Investments
Wisconsin
$10.3M +$1.71M +6,034 +20%
VIM
456
Vinva Investment Management
Australia
$10.2M +$2.6M +9,178 +33%
ANBT
457
American National Bank & Trust
Texas
$10.1M +$279K +984 +3%
AAA
458
Adams Asset Advisors
Texas
$10.1M -$1.03M -3,621 -9%
CCFCSB
459
Cape Cod Five Cents Savings Bank
Massachusetts
$10.1M
BIA
460
Biondo Investment Advisors
Pennsylvania
$10M +$288K +1,015 +3%
CA
461
Clearstead Advisors
Ohio
$9.96M +$500K +1,765 +5%
AA
462
Ancora Advisors
Ohio
$9.92M -$332K -1,173 -3%
PIMJS
463
PKO Investment Management Joint-Stock
Poland
$9.84M +$7.55M +26,660 +310%
ZBNA
464
Zions Bancorporation, National Association
Utah
$9.84M +$1.06M +3,740 +12%
TSW
465
Thompson Siegel & Walmsley
Virginia
$9.83M +$2.27K +8 +0%
AAIM
466
American Assets Investment Management
California
$9.83M
NGA
467
Naples Global Advisors
Florida
$9.82M +$201K +711 +2%
SW
468
SlateStone Wealth
Florida
$9.82M +$102K +361 +1%
OHIS
469
Oak Harvest Investment Services
Texas
$9.8M +$278K +983 +3%
SCM
470
SKBA Capital Management
California
$9.68M +$28.3K +100 +0.3%
RWP
471
RWA Wealth Partners
Massachusetts
$9.67M +$4.53K +16 +0%
AAIM
472
Asset Advisors Investment Management
Georgia
$9.66M -$3.97K -14 -0%
IHL
473
Investment House LLC
California
$9.65M -$256K -903 -3%
FM
474
Foster & Motley
Ohio
$9.62M +$100K +353 +1%
KRS
475
Kentucky Retirement Systems
Kentucky
$9.6M -$638K -2,253 -6%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.