We are live on ! Find out more

2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
Two Sigma Advisers
351
Two Sigma Advisers
New York
$17.3M +$16.6M +57,100 +1,393%
Canada Life
352
Canada Life
Manitoba, Canada
$17.3M +$7.51M +25,886 +70%
MAM
353
Martingale Asset Management
Massachusetts
$17.1M -$1.79M -6,168 -9%
Jane Street
354
Jane Street
New York
$17M +$16M +55,072 +1,078%
YCM
355
Yousif Capital Management
Michigan
$16.9M -$357K -1,231 -2%
LWCFA
356
Loring Wolcott & Coolidge Fiduciary Advisors
Massachusetts
$16.8M -$715K -2,464 -4%
GHA
357
GW Henssler & Associates
Georgia
$16.8M -$101K -348 -0.6%
SF
358
Synovus Financial
Georgia
$16.8M +$152K +524 +0.9%
RIL
359
Rothschild Investment LLC
Illinois
$16.7M -$215K -740 -1%
TF
360
Talbot Financial
Washington
$16.6M +$1.69M +5,839 +11%
MOACM
361
Mutual of America Capital Management
New York
$16.5M -$954K -3,290 -5%
OAM
362
OP Asset Management
$16.5M +$331K +1,141 +2%
HI
363
Horizon Investments
North Carolina
$16.5M +$2.85M +9,823 +20%
CAM
364
Congress Asset Management
Massachusetts
$16.4M -$812K -2,799 -5%
OAM
365
Oak Asset Management
California
$16.4M -$760K -2,619 -4%
LS
366
Livforsakringsbolaget Skandia
Sweden
$16.3M +$406K +1,400 +2%
AAIS
367
ABN AMRO Investment Solutions
$16.2M -$2.38M -8,219 -12%
HIMC
368
Heritage Investors Management Corp
Maryland
$16.2M -$27K -93 -0.2%
EF
369
Empowered Funds
Pennsylvania
$16.2M -$13.2M -45,635 -44%
AF
370
Avanza Fonder
Sweden
$16.1M +$1.32M +4,546 +9%
MIF
371
Mediolanum International Funds
Ireland
$16.1M +$12.9M +44,469 +309%
MR
372
Munich Reinsurance
$16M +$16.4M +56,522 New
TTWM
373
TCV Trust & Wealth Management
Virginia
$15.9M -$225K -775 -1%
Squarepoint
374
Squarepoint
New York
$15.8M +$10.5M +36,170 +181%
PA
375
Profund Advisors
Maryland
$15.8M -$582K -2,008 -3%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.