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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
LA
2876
Legacy Advisors
Pennsylvania
-$2.76M -8,843 Closed
CM
2877
Caption Management
Oklahoma
-$2.14M -7,550 Closed
JWM
2878
Jackson Wealth Management
Florida
-$2.02M -6,474 Closed
MIM
2879
Marshall Investment Management
Colorado
-$1.93M -6,210 Closed
WH
2880
Wallace Hart
Kentucky
-$1.63M -5,229 Closed
1C
2881
111 Capital
France
-$1.58M -5,072 Closed
SMH
2882
Sanders Morris Harris
Texas
-$1.32M -4,292 Closed
AI
2883
AXS Investments
New York
-$1.34M -4,290 Closed
RPAM
2884
Rhenman & Partners Asset Management
Sweden
-$1.25M -4,000 Closed
TL
2885
Tradewinds LLC
North Carolina
-$1.2M -3,852 Closed
PP
2886
PDT Partners
New York
-$1.15M -3,689 Closed
PCH
2887
Polar Capital Holdings
United Kingdom
-$1.13M -3,636 Closed
WA
2888
Win Advisors
Florida
-$1.01M -3,241 Closed
MLA
2889
My Legacy Advisors
Oregon
-$946K -3,035 Closed
BL
2890
Balentine LLC
Georgia
-$855K -2,745 Closed
WCF
2891
West Coast Financial
California
-$841K -2,700 Closed
LA
2892
LM Advisors
California
-$837K -2,686 Closed
HCP
2893
Hexagon Capital Partners
Arkansas
-$832K -2,669 Closed
VCM
2894
Virtue Capital Management
Tennessee
-$828K -2,656 Closed
SIM
2895
Seaview Investment Managers
Florida
-$765K -2,457 Closed
UWS
2896
Unique Wealth Strategies
Illinois
-$737K -2,366 Closed
CAS
2897
CTC Alternative Strategies
Illinois
-$717K -2,300 Closed
WG
2898
Winton Group
United Kingdom
-$676K -2,171 Closed
PA
2899
Prossimo Advisors
California
-$646K -2,074 Closed
SIC
2900
Sterling Investment Counsel
New York
-$645K -2,071 Closed

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.