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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
ATI
2826
Act Two Investors
California
-$12.9M -46,220 Closed
TC
2827
TwinBeech Capital
New York
-$12.1M -43,403 Closed
LF
2828
Longbow Finance
Switzerland
-$7.07M -25,332 Closed
SG
2829
Sienna Gestion
France
-$5.69M -22,311 Closed
TAF
2830
Tredje AP-fonden
Sweden
-$5.25M -18,817 Closed
OTPPB
2831
Ontario Teachers' Pension Plan Board
Ontario, Canada
-$5.06M -18,113 Closed
QCM
2832
Qsemble Capital Management
New York
-$4.14M -14,827 Closed
PAP
2833
Persistent Asset Partners
Hong Kong
-$3.35M -12,000 Closed
XT
2834
XTX Topco
Cayman Islands
-$3.01M -10,774 Closed
SIC
2835
Shoker Investment Counsel
Ohio
-$2.84M -10,174 Closed
ORAM
2836
One River Asset Management
Connecticut
-$2.81M -10,045 Closed
BAM
2837
Bell Asset Management
Australia
-$2.5M -8,964 Closed
Hudson Bay Capital Management
2838
Hudson Bay Capital Management
Connecticut
-$2.39M -8,561 Closed
BMWM
2839
Brown Miller Wealth Management
Virginia
-$2.19M -7,844 Closed
LCM
2840
Legato Capital Management
California
-$2.19M -7,831 Closed
NAM
2841
Nutshell Asset Management
United Kingdom
-$1.84M -6,600 Closed
HIM
2842
Hillsdale Investment Management
Ontario, Canada
-$1.81M -6,490 Closed
Jacobs Levy Equity Management
2843
Jacobs Levy Equity Management
New Jersey
-$1.69M -6,062 Closed
DL
2844
DOHJ LLC
Washington
-$1.66M -5,963 Closed
BCM
2845
Brookmont Capital Management
Texas
-$1.6M -5,720 Closed
ACM
2846
Ayrshire Capital Management
Connecticut
-$1.59M -5,712 Closed
FCM
2847
Fieldview Capital Management
Michigan
-$1.59M -5,694 Closed
FIM
2848
Freedom Investment Management
Connecticut
-$1.49M -5,321 Closed
PR
2849
Payden & Rygel
California
-$1.48M -5,300 Closed
AW
2850
Alaethes Wealth
Nevada
-$1.45M -5,208 Closed

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.