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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
Kovitz Investment Group Partners
251
Kovitz Investment Group Partners
Illinois
$27.4M +$778K +2,682 +3%
Wellington Management Group
252
Wellington Management Group
Massachusetts
$27.4M -$13.5M -46,504 -32%
RPI
253
Railway Pension Investments
United Kingdom
$27.2M +$2.38M +8,200 +9%
UM
254
UniSuper Management
Australia
$27.1M +$2M +6,911 +8%
First Manhattan
255
First Manhattan
New York
$27.1M -$103K -354 -0.4%
SI
256
Stephens Inc
Arkansas
$27M -$74K -255 -0.3%
ATPW
257
Ashton Thomas Private Wealth
Arizona
$26.7M +$773K +2,667 +3%
IMPI
258
Ilmarinen Mutual Pension Insurance
Finland
$26.5M
CBU
259
CIBC Bancorp USA
Illinois
$26.5M +$27.3M +93,962 New
GKIM
260
GW&K Investment Management
Massachusetts
$26.5M -$340K -1,174 -1%
BAMF
261
BI Asset Management Fondsmaeglerselskab
Denmark
$26.3M +$3.03M +10,455 +13%
ZIM
262
Zacks Investment Management
Illinois
$26.3M -$5.51K -19 -0%
IR
263
IAT Reinsurance
New York
$26.1M
BIM
264
Bridges Investment Management
Nebraska
$26M +$294K +1,013 +1%
Pathstone Holdings
265
Pathstone Holdings
New Jersey
$25.9M -$392K -1,352 -1%
CC
266
Cornerstone Capital
California
$25.7M -$247K -852 -0.9%
JE
267
JMAC Enterprises
Pennsylvania
$25.6M +$29K +100 +0.1%
UIM
268
USS Investment Management
United Kingdom
$25.5M
SW
269
SteelPeak Wealth
California
$25.5M -$15.4M -52,953 -37%
DCP
270
Distillate Capital Partners
Illinois
$25.4M -$327K -1,129 -1%
RG
271
Renaissance Group
Kentucky
$25.3M -$4.68M -16,136 -15%
EAM
272
Erste Asset Management
Austria
$25.3M -$7.37M -25,403 -22%
VMPIC
273
Varma Mutual Pension Insurance Co
Finland
$25.2M +$2.12M +7,300 +9%
URS
274
Utah Retirement Systems
Utah
$25.1M +$122K +421 +0.5%
KIA
275
KCM Investment Advisors
California
$25.1M -$302K -1,041 -1%

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.