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2,852 hedge funds and large institutions have $121B invested in Amgen in 2025 Q2 according to their latest regulatory filings, with 145 funds opening new positions, 1,230 increasing their positions, 1,096 reducing their positions, and 182 closing their positions.

New
Increased
Maintained
Reduced
Closed

12% more repeat investments, than reductions

Existing positions increased: 1,230 | Existing positions reduced: 1,096

0.54% more ownership

Funds ownership: 79.82%80.37% (+0.54%)

3% less funds holding

Funds holding: 2,9272,852 (-75)

10% less capital invested

Capital invested by funds: $133B → $121B (-$12.9B)

13% less call options, than puts

Call options by funds: $1.9B | Put options by funds: $2.17B

20% less first-time investments, than exits

New positions opened: 145 | Existing positions closed: 182

46% less funds holding in top 10

Funds holding in top 10: 7440 (-34)

Holders
2,852
Holders Change
-75
Holders Change %
-2.56%
% of All Funds
37.55%
Holding in Top 10
40
Holding in Top 10 Change
-34
Holding in Top 10 Change %
-45.95%
% of All Funds
0.53%
New
145
Increased
1,230
Reduced
1,096
Closed
182
Calls
$1.9B
Puts
$2.17B
Net Calls
-$278M
Net Calls Change
-$472M
Name Holding Trade Value Shares
Change
Change in
Stake
CIC
251
Carnegie Investment Counsel
Ohio
$28.5M +$29.2K +103 +0.1%
MAA
252
Matrix Asset Advisors
New York
$28.4M +$1.21M +4,284 +4%
OSAM
253
O'Shaughnessy Asset Management
Connecticut
$28.2M -$829K -2,926 -3%
QCM
254
QRG Capital Management
Illinois
$27.9M +$918K +3,242 +3%
TWC
255
TD Waterhouse Canada
Ontario, Canada
$27.6M +$1.19M +4,199 +5%
VV
256
Verity & Verity
South Carolina
$27.1M +$261K +923 +1%
First Manhattan
257
First Manhattan
New York
$26.9M -$548K -1,936 -2%
CFB
258
Cullen/Frost Bankers
Texas
$26.8M -$26.3K -93 -0.1%
SI
259
Stephens Inc
Arkansas
$26.7M +$3.37M +11,888 +14%
GKIM
260
GW&K Investment Management
Massachusetts
$26.6M -$2.28M -8,033 -8%
Kovitz Investment Group Partners
261
Kovitz Investment Group Partners
Illinois
$26.4M +$169K +596 +0.6%
IMPI
262
Ilmarinen Mutual Pension Insurance
Finland
$26.2M +$6.23M +22,000 +31%
DZ Bank
263
DZ Bank
Germany
$26.1M +$3.53M +12,462 +15%
ZIM
264
Zacks Investment Management
Illinois
$26M -$363K -1,283 -1%
Pathstone Holdings
265
Pathstone Holdings
New Jersey
$26M -$598K -2,111 -2%
IR
266
IAT Reinsurance
New York
$25.8M
ATPW
267
Ashton Thomas Private Wealth
Arizona
$25.7M +$1.03M +3,633 +4%
CC
268
Cornerstone Capital
California
$25.7M -$1.21M -4,275 -4%
GC
269
Grimes & Company
Massachusetts
$25.6M +$41.1K +145 +0.2%
AWM
270
AE Wealth Management
Kansas
$25.5M +$1.98M +7,001 +8%
BIM
271
Bridges Investment Management
Nebraska
$25.5M -$409K -1,445 -2%
DCP
272
Distillate Capital Partners
Illinois
$25.5M +$25.8M +91,163 New
KAS
273
Kestra Advisory Services
Texas
$25.4M +$791K +2,792 +3%
JE
274
JMAC Enterprises
Pennsylvania
$25.3M +$28.3K +100 +0.1%
UIM
275
USS Investment Management
United Kingdom
$25.2M +$241K +852 +1%

AMGN Hedge Fund Activity: Q2 2025 in Review

2,852 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q2 2025, worth a combined $121B — down 9.7% from $133B a quarter earlier.

Sellers outnumbered buyers: 182 funds closed out of AMGN and 145 opened new positions — a net loss of 37 holders — while 1,096 trimmed existing stakes and 1,230 added.

The largest buyer was Capital International Investors, adding an estimated $1.07B. The largest seller was Primecap Management, cutting an estimated $498M.

  • 2,852 institutional investors held Amgen (AMGN) as of Q2 2025, down from 2,927 in Q1 2025.
  • Funds reported $121B of Amgen stock for Q2 2025, down 9.7% quarter-over-quarter.
  • 145 funds opened new Amgen positions in Q2 2025 and 182 closed out, a net change of -37 holders.
  • The largest Amgen buyer in Q2 2025 was Capital International Investors, an estimated $1.07B added.
  • The largest Amgen seller in Q2 2025 was Primecap Management, an estimated $498M sold.

Based on aggregated 13F filings for Q2 2025.