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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
EA
2676
Evolution Advisers
Virginia
$59K
BI
2677
Binnacle Investments
Iowa
$58.7K +$12.5K +43 +26%
RFG
2678
REAP Financial Group
Texas
$58.7K +$6.96K +24 +13%
TC
2679
Trust Company
Kansas
$57.9K
AIC
2680
Archer Investment Corporation
Indiana
$56.5K +$290 +1 +0.5%
ETS
2681
ESL Trust Services
New York
$56.4K
SIP
2682
Sellwood Investment Partners
Oregon
$56.4K +$58K +200 New
FPF
2683
First Pacific Financial
Washington
$56.4K -$2.61K -9 -4%
OC
2684
Oakmont Corp
California
$55.9K
WA
2685
WPG Advisers
Maryland
$53.9K +$580 +2 +1%
CPG
2686
Cornerstone Planning Group
New Jersey
$53.7K +$23.8K +82 +80%
SC
2687
Solstein Capital
California
$52.5K
STB
2688
S&T Bank
Pennsylvania
$51.9K
FFC
2689
First Financial Corp
Indiana
$50.5K -$20.3K -70 -28%
FDW
2690
Fourth Dimension Wealth
Ohio
$50.5K
CFS
2691
CGC Financial Services
Oregon
$49.4K
TWD
2692
True Wealth Design
Ohio
$47.8K -$3.19K -11 -6%
MSG
2693
Main Street Group
Virginia
$47.2K +$290 +1 +0.6%
WW
2694
Winnow Wealth
Texas
$47K +$48.1K +166 New
TFM
2695
TFC Financial Management
Massachusetts
$46.6K
HC
2696
Hoese & Co
Minnesota
$45.1K
IUHSA
2697
Itau Unibanco Holding S.A.
Brazil
$44K
RA
2698
Rational Advisors
New York
$43.7K +$3.19K +11 +8%
GWSA
2699
Global Wealth Strategies & Associates
Colorado
$43.3K +$5.51K +19 +14%
TCM
2700
Tradewinds Capital Management
Washington
$42.6K

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.