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2,819 hedge funds and large institutions have $119B invested in Amgen in 2025 Q3 according to their latest regulatory filings, with 144 funds opening new positions, 1,122 increasing their positions, 1,153 reducing their positions, and 133 closing their positions.

New
Increased
Maintained
Reduced
Closed

8% more first-time investments, than exits

New positions opened: 144 | Existing positions closed: 133

8% more call options, than puts

Call options by funds: $1.88B | Put options by funds: $1.74B

1% less capital invested

Capital invested by funds: $121B → $119B (-$1.21B)

3% less repeat investments, than reductions

Existing positions increased: 1,122 | Existing positions reduced: 1,153

1% less funds holding

Funds holding: 2,8512,819 (-32)

1.78% less ownership

Funds ownership: 80.37%78.59% (-1.8%)

28% less funds holding in top 10

Funds holding in top 10: 4029 (-11)

Holders
2,819
Holders Change
-32
Holders Change %
-1.12%
% of All Funds
36.99%
Holding in Top 10
29
Holding in Top 10 Change
-11
Holding in Top 10 Change %
-27.5%
% of All Funds
0.38%
New
144
Increased
1,122
Reduced
1,153
Closed
133
Calls
$1.88B
Puts
$1.74B
Net Calls
+$135M
Net Calls Change
+$414M
Name Holding Trade Value Shares
Change
Change in
Stake
SAM
2576
Sherman Asset Management
California
$196K
Loomis, Sayles & Company
2577
Loomis, Sayles & Company
Massachusetts
$195K -$38.9K -134 -16%
RF
2578
Rossby Financial
Florida
$190K +$17.1K +59 +10%
HBT
2579
Hills Bank & Trust
Iowa
$189K
MBFW
2580
Morton Brown Family Wealth
Pennsylvania
$189K
MEG
2581
Millstone Evans Group
Colorado
$188K
DI
2582
DAGCO Inc
Ohio
$187K
BBPWM
2583
Blue Bell Private Wealth Management
Pennsylvania
$185K -$1.45K -5 -0.8%
MTC
2584
Matrix Trust Company
Colorado
$185K +$2.03K +7 +1%
MCI
2585
MRP Capital Investments
Georgia
$181K +$189K +650 New
GTAM
2586
Global Trust Asset Management
Florida
$178K -$29K -100 -14%
CCMI
2587
Creative Capital Management Investments
California
$178K
M
2588
MOTCO
Texas
$175K
C
2589
Covestor
United Kingdom
$173K +$37.7K +130 +27%
CIA
2590
Cape Investment Advisory
Georgia
$172K -$7.54K -26 -4%
TFA
2591
Transamerica Financial Advisors
Florida
$168K +$170K +585 +4,875%
AW
2592
Avion Wealth
Texas
$166K -$3.77K -13 -2%
SL
2593
Salomon & Ludwin
Virginia
$165K +$29K +100 +22%
AP
2594
Aspect Partners
Virginia
$163K -$119K -410 -42%
PWA
2595
Principia Wealth Advisory
Texas
$162K +$2.03K +7 +1%
SWA
2596
SOA Wealth Advisors
New York
$162K +$290 +1 +0.2%
RTC
2597
Riverview Trust Company
Washington
$161K
PB
2598
Pinnacle Bancorp
Nebraska
$156K -$40.6K -140 -20%
CT
2599
Clearstead Trust
Maine
$156K -$8.99K -31 -5%
RWM
2600
RMG Wealth Management
Wisconsin
$155K

AMGN Hedge Fund Activity: Q3 2025 in Review

2,819 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Amgen (AMGN) for Q3 2025, worth a combined $119B — down 1% from $121B a quarter earlier.

Buyers outnumbered sellers: 144 funds opened new AMGN positions and 133 closed out — a net gain of 11 holders — while 1,122 added to existing stakes and 1,153 trimmed.

The largest buyer was Capital World Investors, adding an estimated $561M. The largest seller was Primecap Management, cutting an estimated $268M.

  • 2,819 institutional investors held Amgen (AMGN) as of Q3 2025, down from 2,851 in Q2 2025.
  • Funds reported $119B of Amgen stock for Q3 2025, down 1% quarter-over-quarter.
  • 144 funds opened new Amgen positions in Q3 2025 and 133 closed out, a net change of +11 holders.
  • The largest Amgen buyer in Q3 2025 was Capital World Investors, an estimated $561M added.
  • The largest Amgen seller in Q3 2025 was Primecap Management, an estimated $268M sold.

Based on aggregated 13F filings for Q3 2025.