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ALX Oncology

69 hedge funds and large institutions have $189M invested in ALX Oncology in 2026 Q1 according to their latest regulatory filings, with 25 funds opening new positions, 18 increasing their positions, 11 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

465% more capital invested

Capital invested by funds: $33.5M → $189M (+$156M)

108% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 12

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

64% more repeat investments, than reductions

Existing positions increased: 18 | Existing positions reduced: 11

54% more call options, than puts

Call options by funds: $156K | Put options by funds: $101K

21% more funds holding

Funds holding: 5769 (+12)

17.76% more ownership

Funds ownership: 53.87%71.63% (+18%)

Holders
69
Holders Change
+12
Holders Change %
+21.05%
% of All Funds
0.85%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.02%
New
25
Increased
18
Reduced
11
Closed
12
Calls
$156K
Puts
$101K
Net Calls
+$55K
Net Calls Change
-$89K
Name Holding Trade Value Shares
Change
Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$26.1M +$24.8M +13,011,849 New
TCM
2
TCG Crossover Management
California
$26.1M +$24.8M +13,011,849 New
VP
3
venBio Partners
California
$25.8M +$6.07M +3,184,713 +33%
RG
4
Redmile Group
California
$16M +$8.95M +4,699,470 +144%
Blackstone Inc
5
Blackstone Inc
New York
$11.7M +$11.1M +5,826,544 New
DCM
6
Driehaus Capital Management
Illinois
$11.5M +$8.21M +4,311,738 +303%
VCM
7
Vanguard Capital Management
Pennsylvania
$8.38M +$7.96M +4,179,736 New
Marshall Wace
8
Marshall Wace
United Kingdom
$7.51M +$7.11M +3,730,840 +14,145%
VC
9
Vivo Capital
California
$6.39M +$6.07M +3,184,713 New
AC
10
Almitas Capital
California
$6.36M +$1.21M +636,943 +25%
5VM
11
5AM Venture Management
California
$6.13M +$5.82M +3,057,325 New
O
12
OrbiMed
New York
$5.75M +$5.46M +2,866,256 New
Adage Capital Partners
13
Adage Capital Partners
Massachusetts
$4.01M +$3.81M +2,000,000 New
Millennium Management
14
Millennium Management
New York
$3.99M -$2.32M -1,216,060 -38%
Two Sigma Investments
15
Two Sigma Investments
New York
$3.18M +$1.81M +947,628 +148%
SCM
16
Squadron Capital Management
Illinois
$2.93M +$2.78M +1,460,000 New
Susquehanna International Group
17
Susquehanna International Group
Pennsylvania
$2.66M +$2.24M +1,177,880 +780%
Acadian Asset Management
18
Acadian Asset Management
Massachusetts
$2.2M -$521K -273,248 -20%
Ensign Peak Advisors
19
Ensign Peak Advisors
Utah
$1.91M +$1.81M +950,550 New
UBS Group
20
UBS Group
Switzerland
$1.83M +$92.9K +48,763 +6%
Renaissance Technologies
21
Renaissance Technologies
New York
$1.47M +$590K +309,500 +73%
Bank of America
22
Bank of America
North Carolina
$1.16M +$87.5K +45,938 +9%
Geode Capital Management
23
Geode Capital Management
Massachusetts
$990K +$266K +139,741 +40%
BlackRock
24
BlackRock
New York
$898K -$5.01K -2,631 -0.6%
VFT
25
Vanguard Fiduciary Trust
Pennsylvania
$590K +$561K +294,478 New

ALXO Hedge Fund Activity: Q1 2026 in Review

69 of the 8,126 institutional investors tracked by Wall St. Rank reported a position in ALX Oncology (ALXO) for Q1 2026, worth a combined $189M — up 465% from $33.5M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new ALXO positions and 12 closed out — a net gain of 13 holders — while 18 added to existing stakes and 11 trimmed.

The largest buyer was RA Capital Management, opening a new position worth an estimated $24.8M. The largest seller was Millennium Management, cutting an estimated $2.32M.

  • 69 institutional investors held ALX Oncology (ALXO) as of Q1 2026, up from 57 in Q4 2025.
  • Funds reported $189M of ALX Oncology stock for Q1 2026, up 465% quarter-over-quarter.
  • 25 funds opened new ALX Oncology positions in Q1 2026 and 12 closed out, a net change of +13 holders.
  • The largest ALX Oncology buyer in Q1 2026 was RA Capital Management, an estimated $24.8M added.
  • The largest ALX Oncology seller in Q1 2026 was Millennium Management, an estimated $2.32M sold.

Based on aggregated 13F filings for Q1 2026.