|
1
|
Frazier Management
Seattle,
Washington
|
$43.4M
|
–
|
–
|
–
|
|
|
2
|
TRV GP II
Boston,
Massachusetts
|
$36.4M
|
–
|
–
|
–
|
|
|
3
|
Deer VII & Co
Larchmont,
New York
|
$29.5M
|
–
|
–
|
–
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$24.3M
|
-$4.97M
|
-344,600
|
-16%
|
|
|
5
|
PFM Health Sciences
San Francisco,
California
|
$22.7M
|
+$3.98M
|
+275,911
|
+19%
|
|
|
6
|
Pharmstandard International
Luxembourg
|
$11.4M
|
-$2.29M
|
-159,136
|
-15%
|
|
|
7
|
|
$10.7M
|
+$68.4K
|
+4,741
|
+0.6%
|
|
|
8
|
Wellington Management Group
Boston,
Massachusetts
|
$8.85M
|
-$1.14M
|
-78,800
|
-10%
|
|
|
9
|
|
$7.4M
|
+$4.85M
|
+336,053
|
+145%
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$4.48M
|
+$3.74M
|
+259,414
|
+308%
|
|
|
11
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.46M
|
+$1.73M
|
+120,047
|
+54%
|
|
|
12
|
Partner Investment Management
San Francisco,
California
|
$3.88M
|
-$4M
|
-277,402
|
-48%
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$3.48M
|
-$2.06M
|
-142,850
|
-35%
|
|
|
14
|
Perceptive Advisors
New York
|
$3.26M
|
–
|
–
|
–
|
|
|
15
|
|
$3.12M
|
+$626K
|
+43,439
|
+22%
|
|
|
16
|
Millennium Management
New York
|
$2.86M
|
+$1.84M
|
+127,272
|
+138%
|
|
|
17
|
State Street
Boston,
Massachusetts
|
$2.06M
|
+$1.91M
|
+132,415
|
+517%
|
|
|
18
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$1.52M
|
+$1.59M
|
+110,068
|
+1,582%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$1.49M
|
+$797K
|
+55,238
|
+94%
|
|
|
20
|
Bridgeway Capital Management
Houston,
Texas
|
$1.05M
|
+$288K
|
+20,000
|
+33%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$784K
|
+$709K
|
+49,133
|
+445%
|
|
|
22
|
Bank of New York Mellon
New York
|
$406K
|
+$302K
|
+20,954
|
+206%
|
|
|
23
|
ALPS Advisors
Denver,
Colorado
|
$391K
|
+$433K
|
+30,036
|
New
|
|
|
24
|
Two Sigma Investments
New York
|
$369K
|
+$408K
|
+28,281
|
New
|
|
|
25
|
|
$298K
|
-$90.9K
|
-6,303
|
-22%
|
|
