|
1
|
Frazier Management
Seattle,
Washington
|
$36.7M
|
–
|
–
|
–
|
|
|
2
|
TRV GP II
Boston,
Massachusetts
|
$30.8M
|
–
|
–
|
–
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$23.4M
|
-$3.52M
|
-420,875
|
-16%
|
|
|
4
|
Deer VII & Co
Larchmont,
New York
|
$22.4M
|
–
|
–
|
–
|
|
|
5
|
PFM Health Sciences
San Francisco,
California
|
$15.2M
|
-$2.59K
|
-310
|
-0%
|
|
|
6
|
Pharmstandard International
Luxembourg
|
$11.4M
|
–
|
–
|
–
|
|
|
7
|
|
$9M
|
+$3.7M
|
+442,924
|
+118%
|
|
|
8
|
Wellington Management Group
Boston,
Massachusetts
|
$8.35M
|
–
|
–
|
–
|
|
|
9
|
Partner Investment Management
San Francisco,
California
|
$5.7M
|
–
|
–
|
–
|
|
|
10
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.52M
|
+$712K
|
+85,199
|
+26%
|
|
|
11
|
Perceptive Advisors
New York
|
$2.75M
|
–
|
–
|
–
|
|
|
12
|
|
$2.55M
|
+$40.8K
|
+4,879
|
+2%
|
|
|
13
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.45M
|
+$302K
|
+36,179
|
+19%
|
|
|
14
|
|
$2.16M
|
-$1.35M
|
-162,072
|
-45%
|
|
|
15
|
Millennium Management
New York
|
$1.01M
|
+$582K
|
+69,723
|
+312%
|
|
|
16
|
Adage Capital Partners
Boston,
Massachusetts
|
$927K
|
+$703K
|
+84,160
|
New
|
|
|
17
|
Bridgeway Capital Management
Houston,
Texas
|
$672K
|
+$509K
|
+61,000
|
New
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$648K
|
–
|
–
|
–
|
|
|
19
|
|
$322K
|
-$171K
|
-20,436
|
-41%
|
|
|
20
|
Needham Investment Management
New York
|
$310K
|
–
|
–
|
–
|
|
|
21
|
State Street
Boston,
Massachusetts
|
$282K
|
+$214K
|
+25,624
|
New
|
|
|
22
|
TIAA CREF Investment Management
New York
|
$162K
|
+$59K
|
+7,065
|
+93%
|
|
|
23
|
Citadel Advisors
Miami,
Florida
|
$124K
|
+$94.1K
|
+11,265
|
New
|
|
|
24
|
Geode Capital Management
Boston,
Massachusetts
|
$121K
|
+$92.3K
|
+11,049
|
New
|
|
|
25
|
Bank of New York Mellon
New York
|
$113K
|
+$8
|
+1
|
+0%
|
|
