Alkermes
ALKS
366 hedge funds and large institutions have $5.05B invested in Alkermes in 2025 Q4 according to their latest regulatory filings, with 59 funds opening new positions, 144 increasing their positions, 124 reducing their positions, and 47 closing their positions.
26% more first-time investments, than exits
New positions opened: 59 | Existing positions closed: 47
16% more repeat investments, than reductions
Existing positions increased: 144 | Existing positions reduced: 124
6.49% more ownership
Funds ownership: 102.74% → 109.23% (+6.5%)
2% more funds holding
Funds holding: 358 → 366 (+8)
1% less capital invested
Capital invested by funds: $5.09B → $5.05B (-$40.1M)
67% less funds holding in top 10
Funds holding in top 10: 3 → 1 (-2)
74% less call options, than puts
Call options by funds: $5.84M | Put options by funds: $22.4M
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Wellington Management Group
Boston,
Massachusetts
|
+$79.2M |
| 2 |
DTC
Deep Track Capital
Greenwich,
Connecticut
|
+$59.9M |
| 3 |
BBA
Baker Bros. Advisors
New York
|
+$57.5M |
| 4 |
UBS Group
Zurich,
Switzerland
|
+$53.6M |
| 5 |
American Century Companies
Kansas City,
Missouri
|
+$46.7M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Holocene Advisors
New York
|
-$74.1M |
| 2 |
PBA
Paradigm Biocapital Advisors
New York
|
-$51.6M |
| 3 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$37.1M |
| 4 |
ACA
Avoro Capital Advisors
New York
|
-$25.2M |
| 5 |
Artisan Partners
Milwaukee,
Wisconsin
|
-$22.8M |
ALKS Hedge Fund Activity: Q4 2025 in Review
366 of the 8,267 institutional investors tracked by Wall St. Rank reported a position in Alkermes (ALKS) for Q4 2025, worth a combined $5.05B — down 0.79% from $5.09B a quarter earlier.
Buyers outnumbered sellers: 59 funds opened new ALKS positions and 47 closed out — a net gain of 12 holders — while 144 added to existing stakes and 124 trimmed.
The largest buyer was Wellington Management Group, adding an estimated $79.2M. The largest seller was Holocene Advisors, exiting entirely with an estimated $74.1M sold.
- 366 institutional investors held Alkermes (ALKS) as of Q4 2025, up from 358 in Q3 2025.
- Funds reported $5.05B of Alkermes stock for Q4 2025, down 0.79% quarter-over-quarter.
- 59 funds opened new Alkermes positions in Q4 2025 and 47 closed out, a net change of +12 holders.
- The largest Alkermes buyer in Q4 2025 was Wellington Management Group, an estimated $79.2M added.
- The largest Alkermes seller in Q4 2025 was Holocene Advisors, an estimated $74.1M sold.
Based on aggregated 13F filings for Q4 2025.