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Alkermes

358 hedge funds and large institutions have $5.08B invested in Alkermes in 2025 Q3 according to their latest regulatory filings, with 46 funds opening new positions, 147 increasing their positions, 134 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $27M | Put options by funds: $13.2M

24% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 37

1% more funds holding

Funds holding: 353358 (+5)

10% more repeat investments, than reductions

Existing positions increased: 147 | Existing positions reduced: 134

5% more capital invested

Capital invested by funds: $4.84B → $5.08B (+$239M)

0.12% more ownership

Funds ownership: 102.62%102.74% (+0.12%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

Holders
358
Holders Change
+5
Holders Change %
+1.42%
% of All Funds
4.7%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
46
Increased
147
Reduced
134
Closed
37
Calls
$27M
Puts
$13.2M
Net Calls
+$13.8M
Net Calls Change
+$9.26M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$839M +$3.27M +115,915 +0.4%
Vanguard Group
2
Vanguard Group
Pennsylvania
$545M -$9.12M -323,563 -2%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$307M +$5.54M +196,457 +2%
State Street
4
State Street
Massachusetts
$256M +$9.36M +332,095 +4%
BBA
5
Baker Bros. Advisors
New York
$243M +$47.4M +1,680,748 +26%
Renaissance Technologies
6
Renaissance Technologies
New York
$189M +$13.6M +482,368 +8%
American Century Companies
7
American Century Companies
Missouri
$132M +$20.9M +740,248 +20%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$122M +$1.07M +37,842 +0.9%
JP Morgan Chase
9
JP Morgan Chase
New York
$118M -$25.6M -908,124 -19%
Dimensional Fund Advisors
10
Dimensional Fund Advisors
Texas
$111M +$17M +601,359 +19%
CC
11
Commodore Capital
New York
$92.9M +$18.2M +646,754 +26%
Primecap Management
12
Primecap Management
California
$82.8M -$4.04M -143,430 -5%
Holocene Advisors
13
Holocene Advisors
New York
$74.1M -$10.8M -384,738 -13%
ACA
14
Avoro Capital Advisors
New York
$67.2M -$18.6M -660,000 -23%
N
15
Nuveen
North Carolina
$65.2M +$3.54M +125,403 +6%
Charles Schwab
16
Charles Schwab
California
$64.2M +$1.36M +48,324 +2%
Artisan Partners
17
Artisan Partners
Wisconsin
$63.3M +$16M +567,965 +37%
Loomis, Sayles & Company
18
Loomis, Sayles & Company
Massachusetts
$61.5M -$1.72M -61,043 -3%
Goldman Sachs
19
Goldman Sachs
New York
$59.8M +$9.23M +327,248 +20%
Northern Trust
20
Northern Trust
Illinois
$53M -$1.34M -47,429 -3%
PBA
21
Paradigm Biocapital Advisors
New York
$51.6M +$9.69M +343,765 +25%
RI
22
RTW Investments
New York
$50.2M -$84.9M -3,009,933 -64%
Morgan Stanley
23
Morgan Stanley
New York
$46.5M -$7.06M -250,553 -14%
Bank of New York Mellon
24
Bank of New York Mellon
New York
$42.7M -$3.14M -111,420 -7%
First Trust Advisors
25
First Trust Advisors
Illinois
$41.9M +$20.9K +740 +0.1%

ALKS Hedge Fund Activity: Q3 2025 in Review

358 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Alkermes (ALKS) for Q3 2025, worth a combined $5.08B — up 4.9% from $4.84B a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new ALKS positions and 37 closed out — a net gain of 9 holders — while 147 added to existing stakes and 134 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $47.4M. The largest seller was RTW Investments, cutting an estimated $84.9M.

  • 358 institutional investors held Alkermes (ALKS) as of Q3 2025, up from 353 in Q2 2025.
  • Funds reported $5.08B of Alkermes stock for Q3 2025, up 4.9% quarter-over-quarter.
  • 46 funds opened new Alkermes positions in Q3 2025 and 37 closed out, a net change of +9 holders.
  • The largest Alkermes buyer in Q3 2025 was Baker Bros. Advisors, an estimated $47.4M added.
  • The largest Alkermes seller in Q3 2025 was RTW Investments, an estimated $84.9M sold.

Based on aggregated 13F filings for Q3 2025.