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Alkermes

358 hedge funds and large institutions have $5.08B invested in Alkermes in 2025 Q3 according to their latest regulatory filings, with 46 funds opening new positions, 147 increasing their positions, 134 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

105% more call options, than puts

Call options by funds: $27M | Put options by funds: $13.2M

24% more first-time investments, than exits

New positions opened: 46 | Existing positions closed: 37

1% more funds holding

Funds holding: 353358 (+5)

10% more repeat investments, than reductions

Existing positions increased: 147 | Existing positions reduced: 134

5% more capital invested

Capital invested by funds: $4.84B → $5.08B (+$239M)

0.12% more ownership

Funds ownership: 102.62%102.74% (+0.12%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

Holders
358
Holders Change
+5
Holders Change %
+1.42%
% of All Funds
4.7%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
46
Increased
147
Reduced
134
Closed
37
Calls
$27M
Puts
$13.2M
Net Calls
+$13.8M
Net Calls Change
+$9.26M
Name Holding Trade Value Shares
Change
Change in
Stake
MB
51
MPM BioImpact
Massachusetts
$16.5M
VOYA Investment Management
52
VOYA Investment Management
Georgia
$16M +$848K +30,065 +6%
D.E. Shaw & Co
53
D.E. Shaw & Co
New York
$15.9M -$8.21M -291,347 -36%
Allianz Asset Management
54
Allianz Asset Management
Germany
$15.7M +$14.4M +511,702 +3,908%
EC
55
EcoR1 Capital
California
$15M
Legal & General Group
56
Legal & General Group
United Kingdom
$15M -$1.01M -35,719 -7%
RhumbLine Advisers
57
RhumbLine Advisers
Massachusetts
$14.2M +$27.6K +980 +0.2%
GIM
58
Glenmede Investment Management
Pennsylvania
$13.7M -$782K -27,722 -6%
OM
59
Opaleye Management
Massachusetts
$13.5M +$12.7M +450,000 New
Raymond James Financial
60
Raymond James Financial
Florida
$13.4M -$211K -7,492 -2%
Squarepoint
61
Squarepoint
New York
$13.4M +$11.2M +396,039 +804%
Mackenzie Financial
62
Mackenzie Financial
Ontario, Canada
$13.3M +$4.29M +152,023 +52%
Royal Bank of Canada
63
Royal Bank of Canada
Ontario, Canada
$12.6M +$5.44M +192,848 +85%
Canada Pension Plan Investment Board
64
Canada Pension Plan Investment Board
Ontario, Canada
$12.5M +$1.27M +44,900 +12%
UBS AM
65
UBS AM
Illinois
$11.8M -$7.87M -279,002 -42%
Jane Street
66
Jane Street
New York
$11.8M +$989K +35,084 +10%
RHJA
67
Rice Hall James & Associates
California
$11.6M -$1.03M -36,543 -9%
Wellington Management Group
68
Wellington Management Group
Massachusetts
$11.3M -$37.4M -1,324,913 -78%
Macquarie Group
69
Macquarie Group
Australia
$11.2M -$40.4K -1,434 -0.4%
AQR Capital Management
70
AQR Capital Management
Connecticut
$11.2M -$2.26M -80,100 -18%
Janus Henderson Group
71
Janus Henderson Group
United Kingdom
$10.3M +$3.94M +139,895 +68%
Victory Capital Management
72
Victory Capital Management
Texas
$10.3M +$2.93M +103,749 +43%
Handelsbanken Fonder
73
Handelsbanken Fonder
Sweden
$9.96M +$386K +13,700 +4%
Fisher Asset Management
74
Fisher Asset Management
Washington
$9.68M +$868K +30,801 +11%
California Public Employees Retirement System
75
California Public Employees Retirement System
California
$9.63M +$348K +12,337 +4%

ALKS Hedge Fund Activity: Q3 2025 in Review

358 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Alkermes (ALKS) for Q3 2025, worth a combined $5.08B — up 4.9% from $4.84B a quarter earlier.

Buyers outnumbered sellers: 46 funds opened new ALKS positions and 37 closed out — a net gain of 9 holders — while 147 added to existing stakes and 134 trimmed.

The largest buyer was Baker Bros. Advisors, adding an estimated $47.4M. The largest seller was RTW Investments, cutting an estimated $84.9M.

  • 358 institutional investors held Alkermes (ALKS) as of Q3 2025, up from 353 in Q2 2025.
  • Funds reported $5.08B of Alkermes stock for Q3 2025, up 4.9% quarter-over-quarter.
  • 46 funds opened new Alkermes positions in Q3 2025 and 37 closed out, a net change of +9 holders.
  • The largest Alkermes buyer in Q3 2025 was Baker Bros. Advisors, an estimated $47.4M added.
  • The largest Alkermes seller in Q3 2025 was RTW Investments, an estimated $84.9M sold.

Based on aggregated 13F filings for Q3 2025.