We are live on ! Find out more
ALKS icon

Alkermes

353 hedge funds and large institutions have $4.84B invested in Alkermes in 2025 Q2 according to their latest regulatory filings, with 42 funds opening new positions, 154 increasing their positions, 120 reducing their positions, and 55 closing their positions.

New
Increased
Maintained
Reduced
Closed

41% more call options, than puts

Call options by funds: $15.5M | Put options by funds: $11M

28% more repeat investments, than reductions

Existing positions increased: 154 | Existing positions reduced: 120

3.33% less ownership

Funds ownership: 105.95%102.62% (-3.3%)

5% less funds holding

Funds holding: 371353 (-18)

15% less capital invested

Capital invested by funds: $5.69B → $4.84B (-$847M)

24% less first-time investments, than exits

New positions opened: 42 | Existing positions closed: 55

33% less funds holding in top 10

Funds holding in top 10: 64 (-2)

Holders
353
Holders Change
-18
Holders Change %
-4.85%
% of All Funds
4.65%
Holding in Top 10
4
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-33.33%
% of All Funds
0.05%
New
42
Increased
154
Reduced
120
Closed
55
Calls
$15.5M
Puts
$11M
Net Calls
+$4.53M
Net Calls Change
+$11.1M
Name Holding Trade Value Shares
Change
Change in
Stake
Bank of New York Mellon
26
Bank of New York Mellon
New York
$43.9M -$4.59M -154,309 -9%
First Trust Advisors
27
First Trust Advisors
Illinois
$40M -$6.66M -223,765 -14%
PBA
28
Paradigm Biocapital Advisors
New York
$39.4M +$40.9M +1,375,569 New
UBS Group
29
UBS Group
Switzerland
$38.4M -$50.6M -1,700,807 -56%
Fidelity Investments
30
Fidelity Investments
Massachusetts
$36.6M -$7.89M -265,052 -17%
BNP Paribas Financial Markets
31
BNP Paribas Financial Markets
France
$32.5M +$30M +1,007,488 +787%
FLSM
32
Frazier Life Sciences Management
California
$28.6M +$11.9M +399,518 +66%
AAA
33
Affinity Asset Advisors
New York
$28.6M
Principal Financial Group
34
Principal Financial Group
Iowa
$26.2M -$419K -14,070 -2%
Pacer Advisors
35
Pacer Advisors
Pennsylvania
$25.9M +$500K +16,813 +2%
PAM
36
Panagora Asset Management
Massachusetts
$25.1M +$512K +17,192 +2%
DCM
37
Driehaus Capital Management
Illinois
$23.7M +$1.01M +33,980 +4%
D.E. Shaw & Co
38
D.E. Shaw & Co
New York
$23.5M +$10.5M +351,615 +75%
Ameriprise
39
Ameriprise
Minnesota
$20.2M +$5.22M +175,235 +33%
Barclays
40
Barclays
United Kingdom
$19.9M +$8.16M +274,171 +65%
FCM
41
Farallon Capital Management
California
$19.8M -$20.8M -698,137 -50%
Acadian Asset Management
42
Acadian Asset Management
Massachusetts
$19.6M -$5.79M -194,575 -22%
UBS AM
43
UBS AM
Illinois
$19.2M +$5.63M +189,097 +39%
MIM
44
MetLife Investment Management
New Jersey
$18.8M +$2.65M +89,027 +16%
Public Sector Pension Investment Board (PSP Investments)
45
Public Sector Pension Investment Board (PSP Investments)
Quebec, Canada
$18.2M +$1.54M +51,651 +9%
Invesco
46
Invesco
Georgia
$17.5M -$3.64M -122,473 -17%
SBH
47
Segall Bryant & Hamill
Illinois
$17M +$1.94M +65,117 +12%
WP
48
Woodline Partners
California
$16M -$5.52M -185,535 -25%
MB
49
MPM BioImpact
Massachusetts
$15.7M +$6.3M +211,659 +63%
Legal & General Group
50
Legal & General Group
United Kingdom
$15.3M -$513K -17,227 -3%

ALKS Hedge Fund Activity: Q2 2025 in Review

353 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Alkermes (ALKS) for Q2 2025, worth a combined $4.84B — down 15% from $5.69B a quarter earlier.

Sellers outnumbered buyers: 55 funds closed out of ALKS and 42 opened new positions — a net loss of 13 holders — while 120 trimmed existing stakes and 154 added.

The largest buyer was Baker Bros. Advisors, adding an estimated $57.4M. The largest seller was RTW Investments, cutting an estimated $65.5M.

  • 353 institutional investors held Alkermes (ALKS) as of Q2 2025, down from 371 in Q1 2025.
  • Funds reported $4.84B of Alkermes stock for Q2 2025, down 15% quarter-over-quarter.
  • 42 funds opened new Alkermes positions in Q2 2025 and 55 closed out, a net change of -13 holders.
  • The largest Alkermes buyer in Q2 2025 was Baker Bros. Advisors, an estimated $57.4M added.
  • The largest Alkermes seller in Q2 2025 was RTW Investments, an estimated $65.5M sold.

Based on aggregated 13F filings for Q2 2025.