|
1
|
|
$146M
|
-$64.9M
|
-2,352,369
|
-28%
|
|
|
2
|
|
$126M
|
+$25.8M
|
+934,409
|
+22%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$119M
|
+$14.9M
|
+539,724
|
+13%
|
|
|
4
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$104M
|
-$4.48M
|
-162,343
|
-4%
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$101M
|
–
|
–
|
–
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$85.1M
|
-$3.2M
|
-115,960
|
-3%
|
|
|
7
|
Gilder Gagnon Howe & Co
New York
|
$62.5M
|
-$4.66M
|
-168,927
|
-6%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$44.2M
|
+$18.7M
|
+676,606
|
+60%
|
|
|
9
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$42M
|
+$21.8M
|
+790,531
|
+85%
|
|
|
10
|
Deerfield Management
New York
|
$41M
|
-$1.71M
|
-62,000
|
-4%
|
|
|
11
|
|
$40.1M
|
+$1.73M
|
+62,526
|
+4%
|
|
|
12
|
|
$26.3M
|
–
|
–
|
–
|
|
|
13
|
Bank of New York Mellon
New York
|
$24M
|
+$18M
|
+653,640
|
+200%
|
|
|
14
|
Avidity Partners Management
Dallas,
Texas
|
$16.8M
|
-$762K
|
-27,600
|
-4%
|
|
|
15
|
Geode Capital Management
Boston,
Massachusetts
|
$15.9M
|
+$2.73M
|
+98,830
|
+18%
|
|
|
16
|
Northern Trust
Chicago,
Illinois
|
$14.7M
|
+$4.09M
|
+148,103
|
+33%
|
|
|
17
|
|
$13.5M
|
+$1.05M
|
+37,983
|
+7%
|
|
|
18
|
Perceptive Advisors
New York
|
$12.5M
|
–
|
–
|
–
|
|
|
19
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$12.1M
|
+$3.75M
|
+135,838
|
+38%
|
|
|
20
|
|
$11.4M
|
+$58K
|
+2,100
|
+0.5%
|
|
|
21
|
Holocene Advisors
New York
|
$8.36M
|
-$1.55M
|
-56,255
|
-14%
|
|
|
22
|
New Leaf Venture Partners
New York
|
$8.3M
|
-$8.28M
|
-300,000
|
-47%
|
|
|
23
|
Adage Capital Partners
Boston,
Massachusetts
|
$7.33M
|
-$2.76M
|
-100,000
|
-25%
|
|
|
24
|
Franklin Resources
San Mateo,
California
|
$7.29M
|
–
|
–
|
–
|
|
|
25
|
Point72 Asset Management
Stamford,
Connecticut
|
$7.04M
|
+$7.96M
|
+288,263
|
New
|
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