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Alector
ALEC

Name Holding Trade Value Shares
Change 		Change in
Stake
O
1
OrbiMed
New York
$247M +$249M +13,182,329 New
DM
2
Deerfield Management
New York
$36.6M +$37M +1,956,923 New
AI
3
Alphabet Inc
California
$22M +$22.2M +1,174,540 New
Federated Hermes
4
Federated Hermes
Pennsylvania
$22M +$22.2M +1,173,338 New
Fidelity Investments
5
Fidelity Investments
Massachusetts
$20.9M +$21.1M +1,114,436 New
RCM
6
RA Capital Management
Massachusetts
$18.7M +$18.9M +1,000,000 New
Vanguard Group
7
Vanguard Group
Pennsylvania
$16.2M +$16.4M +865,736 New
HCM
8
Highline Capital Management
New York
$15.4M +$15.5M +820,290 New
NLVP
9
New Leaf Venture Partners
New York
$14.7M +$14.9M +787,769 New
Millennium Management
10
Millennium Management
New York
$14.1M +$14.3M +753,611 New
FCMI
11
Foresite Capital Management IV
California
$10.7M +$22.8M +1,203,462 New
Goldman Sachs
12
Goldman Sachs
New York
$9.7M +$9.8M +517,942 New
PA
13
Perceptive Advisors
New York
$9.58M +$9.68M +511,731 New
Franklin Resources
14
Franklin Resources
California
$9.36M +$9.46M +500,000 New
Lord, Abbett & Co
15
Lord, Abbett & Co
New Jersey
$9.25M +$9.35M +494,126 New
BlackRock
16
BlackRock
New York
$8.22M +$8.31M +439,178 New
CC
17
Casdin Capital
New York
$6.2M +$6.26M +331,039 New
AG
18
Artal Group
Luxembourg
$4.68M +$4.73M +250,000 New
LCM
19
Laurion Capital Management
New York
$4.68M +$4.73M +250,000 New
GGHC
20
Gilder Gagnon Howe & Co
New York
$4.09M +$4.13M +218,385 New
ACP
21
Acuta Capital Partners
California
$3.74M +$3.78M +200,000 New
Geode Capital Management
22
Geode Capital Management
Massachusetts
$2.47M +$2.5M +132,154 New
PIM
23
Platinum Investment Management
Australia
$2.46M +$2.49M +131,578 New
Alyeska Investment Group
24
Alyeska Investment Group
Illinois
$2.3M +$2.32M +122,883 New
Northern Trust
25
Northern Trust
Illinois
$1.87M +$1.89M +100,157 New
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