Alector
ALEC
149 hedge funds and large institutions have $221M invested in Alector in 2025 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 46 increasing their positions, 40 reducing their positions, and 12 closing their positions.
139% more call options, than puts
Call options by funds: $1.93M | Put options by funds: $807K
124% more capital invested
Capital invested by funds: $98.7M → $221M (+$123M)
108% more first-time investments, than exits
New positions opened: 25 | Existing positions closed: 12
100% more funds holding in top 10
Funds holding in top 10: 3 → 6 (+3)
15% more repeat investments, than reductions
Existing positions increased: 46 | Existing positions reduced: 40
10% more funds holding
Funds holding: 136 → 149 (+13)
3.34% more ownership
Funds ownership: 70.51% → 73.85% (+3.3%)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RI
RTW Investments
New York
|
+$15.4M |
| 2 |
6CM
683 Capital Management
New York
|
+$2.2M |
| 3 |
Millennium Management
New York
|
+$1.64M |
| 4 |
Barclays
London,
United Kingdom
|
+$1.55M |
| 5 |
D.E. Shaw & Co
New York
|
+$978K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
T. Rowe Price Associates
Baltimore,
Maryland
|
-$5.93M |
| 2 |
ACM
ADAR1 Capital Management
Austin,
Texas
|
-$2.41M |
| 3 |
BlackRock
New York
|
-$1.71M |
| 4 |
SCM
Sio Capital Management
New York
|
-$1.18M |
| 5 |
EP
Eversept Partners
New York
|
-$1.1M |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
151
Walleye Capital
New York
| – | -$373K | -266,204 | Closed |
|
|
SOW
152
State of Wyoming
Cheyenne,
Wyoming
| – | -$312K | -223,092 | Closed |
|
|
GCP
153
GSA Capital Partners
London,
United Kingdom
| – | -$211K | -150,669 | Closed |
|
|
SFI
154
Susquehanna Fundamental Investments
Bala Cynwyd,
Pennsylvania
| – | -$99.1K | -70,778 | Closed |
|
|
AG
155
Algert Global
San Francisco,
California
| – | -$62K | -44,460 | Closed |
|
156
State Board of Administration of Florida Retirement System
Tallahassee,
Florida
| – | -$35.8K | -25,570 | Closed |
|
|
SAM
157
Shell Asset Management
The Hague,
Netherlands
| – | -$19K | -13,887 | Closed |
|
158
US Bancorp
Minneapolis,
Minnesota
| – | -$17.4K | -12,427 | Closed |
|
159
Raymond James Financial
St Petersburg,
Florida
| – | -$2.07K | -1,479 | Closed |
|
|
BIG
160
Brooklyn Investment Group
Brooklyn,
New York
| – | -$842 | -601 | Closed |
|
|
AW
161
Avion Wealth
The Woodlands,
Texas
| – | +$740 | +336 | New |
|
ALEC Hedge Fund Activity: Q3 2025 in Review
149 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Alector (ALEC) for Q3 2025, worth a combined $221M — up 124% from $98.7M a quarter earlier.
Buyers outnumbered sellers: 25 funds opened new ALEC positions and 12 closed out — a net gain of 13 holders — while 46 added to existing stakes and 40 trimmed.
The largest buyer was RTW Investments, opening a new position worth an estimated $15.4M. The largest seller was T. Rowe Price Associates, cutting an estimated $5.93M.
- 149 institutional investors held Alector (ALEC) as of Q3 2025, up from 136 in Q2 2025.
- Funds reported $221M of Alector stock for Q3 2025, up 124% quarter-over-quarter.
- 25 funds opened new Alector positions in Q3 2025 and 12 closed out, a net change of +13 holders.
- The largest Alector buyer in Q3 2025 was RTW Investments, an estimated $15.4M added.
- The largest Alector seller in Q3 2025 was T. Rowe Price Associates, an estimated $5.93M sold.
Based on aggregated 13F filings for Q3 2025.