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Alector
ALEC

141 hedge funds and large institutions have $89.8M invested in Alector in 2025 Q1 according to their latest regulatory filings, with 19 funds opening new positions, 45 increasing their positions, 35 reducing their positions, and 28 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,286% more call options, than puts

Call options by funds: $402K | Put options by funds: $29K

29% more repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 35

0% more funds holding in top 10

Funds holding in top 10: 3 → 3 (0)

1.72% less ownership

Funds ownership: 75% → 73.28% (-1.7%)

6% less funds holding

Funds holding: 150 → 141 (-9)

32% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 28

35% less capital invested

Capital invested by funds: $139M → $89.8M (-$49M)

Holders
141
Holders Change
-9
Holders Change %
-6%
% of All Funds
1.89%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
19
Increased
45
Reduced
35
Closed
28
Calls
$402K
Puts
$29K
Net Calls
+$373K
Net Calls Change
+$131K

Top Buyers

1
VPC
Vestal Point Capital
New York
+$821K
2
Vanguard Group
Vanguard Group
Pennsylvania
+$711K
3
EP
Eversept Partners
New York
+$679K
4
Acadian Asset Management
Acadian Asset Management
Massachusetts
+$668K
5
Jacobs Levy Equity Management
Jacobs Levy Equity Management
New Jersey
+$447K

Top Sellers

1
BlackRock
BlackRock
New York
-$1.4M
2
Citadel Advisors
Citadel Advisors
Florida
-$683K
3
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
-$639K
4
Morgan Stanley
Morgan Stanley
New York
-$495K
5
Fidelity Investments
Fidelity Investments
Massachusetts
-$488K
Name Holding Trade Value Shares
Change 		Change in
Stake
SFI
51
Susquehanna Fundamental Investments
Pennsylvania
$170K -$11.6K -7,133 -5%
Barclays
52
Barclays
United Kingdom
$154K -$83.8K -51,483 -29%
Manulife (Manufacturers Life Insurance)
53
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$152K +$1.49K +916 +0.7%
RhumbLine Advisers
54
RhumbLine Advisers
Massachusetts
$143K +$1.21K +740 +0.6%
TD Asset Management
55
TD Asset Management
Ontario, Canada
$137K – – –
SFM
56
Sphera Funds Management
Israel
$134K -$351K -215,431 -66%
PAP
57
Persistent Asset Partners
Hong Kong
$129K +$171K +104,927 New
DekaBank Deutsche Girozentrale
58
DekaBank Deutsche Girozentrale
Germany
$127K – – –
SO
59
STRS Ohio
Ohio
$126K – – –
CM
60
Cercano Management
Washington
$115K – – –
UBS Group
61
UBS Group
Switzerland
$102K -$57.1K -35,064 -30%
AllianceBernstein
62
AllianceBernstein
Tennessee
$101K – – –
IC
63
IEQ Capital
California
$98.9K +$131K +80,406 New
AA
64
ALPS Advisors
Colorado
$92.2K -$6.81K -4,182 -5%
Mirae Asset Global ETFs Holdings
65
Mirae Asset Global ETFs Holdings
Hong Kong
$91.8K +$2.43K +1,495 +2%
Citigroup
66
Citigroup
New York
$77.2K -$11.4K -7,017 -10%
CS
67
Cannell & Spears
New York
$75.8K – – –
IIM
68
INTECH Investment Management
Florida
$74.7K +$41.3K +25,369 +72%
SG Americas Securities
69
SG Americas Securities
New York
$74K +$34K +20,914 +53%
HSBC Holdings
70
HSBC Holdings
United Kingdom
$72.9K +$145 +89 +0.2%
Squarepoint
71
Squarepoint
New York
$72.8K +$75.1K +46,100 +352%
Marshall Wace
72
Marshall Wace
United Kingdom
$72.7K +$17.3K +10,651 +22%
VCIM
73
Velan Capital Investment Management
Georgia
$67.7K – – –
Russell Investments Group
74
Russell Investments Group
United Kingdom
$65.7K -$4.59K -2,818 -5%
URS
75
Utah Retirement Systems
Utah
$63.3K – – –
1 2
3
4 5

ALEC Hedge Fund Activity: Q1 2025 in Review

141 of the 7,457 institutional investors tracked by Wall St. Rank reported a position in Alector (ALEC) for Q1 2025, worth a combined $89.8M — down 35% from $139M a quarter earlier.

Sellers outnumbered buyers: 28 funds closed out of ALEC and 19 opened new positions — a net loss of 9 holders — while 35 trimmed existing stakes and 45 added.

The largest buyer was Vestal Point Capital, opening a new position worth an estimated $821K. The largest seller was BlackRock, cutting an estimated $1.4M.

  • 141 institutional investors held Alector (ALEC) as of Q1 2025, down from 150 in Q4 2024.
  • Funds reported $89.8M of Alector stock for Q1 2025, down 35% quarter-over-quarter.
  • 19 funds opened new Alector positions in Q1 2025 and 28 closed out, a net change of -9 holders.
  • The largest Alector buyer in Q1 2025 was Vestal Point Capital, an estimated $821K added.
  • The largest Alector seller in Q1 2025 was BlackRock, an estimated $1.4M sold.

Based on aggregated 13F filings for Q1 2025.