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Alector

149 hedge funds and large institutions have $221M invested in Alector in 2025 Q3 according to their latest regulatory filings, with 25 funds opening new positions, 46 increasing their positions, 40 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed

139% more call options, than puts

Call options by funds: $1.93M | Put options by funds: $807K

124% more capital invested

Capital invested by funds: $98.7M → $221M (+$123M)

108% more first-time investments, than exits

New positions opened: 25 | Existing positions closed: 12

100% more funds holding in top 10

Funds holding in top 10: 36 (+3)

15% more repeat investments, than reductions

Existing positions increased: 46 | Existing positions reduced: 40

10% more funds holding

Funds holding: 136149 (+13)

3.34% more ownership

Funds ownership: 70.51%73.85% (+3.3%)

Holders
149
Holders Change
+13
Holders Change %
+9.56%
% of All Funds
1.96%
Holding in Top 10
6
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+100%
% of All Funds
0.08%
New
25
Increased
46
Reduced
40
Closed
12
Calls
$1.93M
Puts
$807K
Net Calls
+$1.13M
Net Calls Change
+$915K
Name Holding Trade Value Shares
Change
Change in
Stake
Northern Trust
26
Northern Trust
Illinois
$1.88M -$53.9K -24,452 -4%
Royal Bank of Canada
27
Royal Bank of Canada
Ontario, Canada
$1.86M +$576K +261,464 +71%
Goldman Sachs
28
Goldman Sachs
New York
$1.81M +$519K +235,432 +63%
BFM
29
Boothbay Fund Management
New York
$1.55M +$144K +65,214 +14%
Two Sigma Advisers
30
Two Sigma Advisers
New York
$1.53M +$309K +140,400 +37%
MC
31
Medici Capital
California
$1.43M +$693K +314,783 +188%
Citadel Advisors
32
Citadel Advisors
Florida
$1.4M -$177K -80,239 -15%
AQR Capital Management
33
AQR Capital Management
Connecticut
$1.3M +$69.3K +31,469 +8%
Morgan Stanley
34
Morgan Stanley
New York
$1.29M -$380K -172,384 -28%
Jane Street
35
Jane Street
New York
$1.04M +$719K +326,279 +1,362%
NLVP
36
New Leaf Venture Partners
New York
$1.01M
Susquehanna International Group
37
Susquehanna International Group
Pennsylvania
$914K +$231K +104,862 +51%
Two Sigma Investments
38
Two Sigma Investments
New York
$909K +$187K +85,040 +38%
Dimensional Fund Advisors
39
Dimensional Fund Advisors
Texas
$876K -$193K -87,485 -23%
Mackenzie Financial
40
Mackenzie Financial
Ontario, Canada
$840K +$20.4K +9,270 +3%
Ameriprise
41
Ameriprise
Minnesota
$811K +$573K +259,907 +1,839%
TD Asset Management
42
TD Asset Management
Ontario, Canada
$810K -$833K -378,000 -58%
Bank of America
43
Bank of America
North Carolina
$729K -$215K -97,626 -28%
UBS Group
44
UBS Group
Switzerland
$682K +$416K +188,606 +450%
Bank of New York Mellon
45
Bank of New York Mellon
New York
$664K -$97.8K -44,388 -17%
Manulife (Manufacturers Life Insurance)
46
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$641K -$214K -97,004 -31%
Invesco
47
Invesco
Georgia
$569K +$36.4K +16,510 +9%
AI
48
Alphabet Inc
California
$521K
Marshall Wace
49
Marshall Wace
United Kingdom
$449K +$334K +151,643 New
JP Morgan Chase
50
JP Morgan Chase
New York
$404K +$200K +90,894 +200%

ALEC Hedge Fund Activity: Q3 2025 in Review

149 of the 7,619 institutional investors tracked by Wall St. Rank reported a position in Alector (ALEC) for Q3 2025, worth a combined $221M — up 124% from $98.7M a quarter earlier.

Buyers outnumbered sellers: 25 funds opened new ALEC positions and 12 closed out — a net gain of 13 holders — while 46 added to existing stakes and 40 trimmed.

The largest buyer was RTW Investments, opening a new position worth an estimated $15.4M. The largest seller was T. Rowe Price Associates, cutting an estimated $5.93M.

  • 149 institutional investors held Alector (ALEC) as of Q3 2025, up from 136 in Q2 2025.
  • Funds reported $221M of Alector stock for Q3 2025, up 124% quarter-over-quarter.
  • 25 funds opened new Alector positions in Q3 2025 and 12 closed out, a net change of +13 holders.
  • The largest Alector buyer in Q3 2025 was RTW Investments, an estimated $15.4M added.
  • The largest Alector seller in Q3 2025 was T. Rowe Price Associates, an estimated $5.93M sold.

Based on aggregated 13F filings for Q3 2025.