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Alector
ALEC

Overview Fund Activity

135 hedge funds and large institutions have $98.7M invested in Alector in 2025 Q2 according to their latest regulatory filings, with 16 funds opening new positions, 46 increasing their positions, 38 reducing their positions, and 23 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
135
Holders Change
-7
Holders Change %
-4.93%
% of All Funds
1.81%
Holding in Top 10
3
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.04%
New
16
Increased
46
Reduced
38
Closed
23
Calls
$229K
Puts
$19K
Net Calls
+$210K
Net Calls Change
-$163K

Top Buyers

1
T. Rowe Price Associates
1
T. Rowe Price Associates
Maryland
$6.83M
2
EP
2
Eversept Partners
New York
$2.78M
3
ACM
3
ADAR1 Capital Management
Texas
$2.41M
4
Acadian Asset Management
4
Acadian Asset Management
Massachusetts
$3.03M
5
Fidelity Investments
5
Fidelity Investments
Massachusetts
$21M

Top Sellers

1
RCM
1
RA Capital Management
Massachusetts
$0
2
JPMorgan Chase & Co
2
JPMorgan Chase & Co
New York
$63.7K
3
Franklin Resources
3
Franklin Resources
California
$0
4
BlackRock
4
BlackRock
New York
$11.2M
5
AC
5
Almitas Capital
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
D.E. Shaw & Co
26
D.E. Shaw & Co
New York
$748K +$90.9K +64,899 +14%
PAM
27
Panagora Asset Management
Massachusetts
$723K +$210K +150,135 +41%
BFM
28
Boothbay Fund Management
New York
$642K +$258K +184,503 +67%
Millennium Management
29
Millennium Management
New York
$575K +$204K +145,987 +55%
AQR Capital Management
30
AQR Capital Management
Connecticut
$569K -$120K -85,974 -17%
Dimensional Fund Advisors
31
Dimensional Fund Advisors
Texas
$537K -$148K -106,003 -22%
Two Sigma Advisers
32
Two Sigma Advisers
New York
$528K -$22.3K -15,900 -4%
Goldman Sachs
33
Goldman Sachs
New York
$524K +$87.3K +62,332 +20%
Royal Bank of Canada
34
Royal Bank of Canada
Ontario, Canada
$513K +$506K +362,395 +7,561%
Bank of America
35
Bank of America
North Carolina
$481K +$8.3K +5,927 +2%
NLVP
36
New Leaf Venture Partners
New York
$475K – – –
Manulife (Manufacturers Life Insurance)
37
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$439K +$266K +189,686 +153%
Mackenzie Financial
38
Mackenzie Financial
Ontario, Canada
$384K +$384K +274,442 New
Bank of New York Mellon
39
Bank of New York Mellon
New York
$376K +$27.1K +19,378 +8%
Walleye Capital
40
Walleye Capital
New York
$373K -$55.2K -39,397 -13%
DP
41
Diadema Partners
New Jersey
$372K -$267K -190,523 -42%
SOW
42
State of Wyoming
Wyoming
$312K +$36.8K +26,278 +13%
Two Sigma Investments
43
Two Sigma Investments
New York
$311K +$10.8K +7,714 +4%
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$285K -$69K -49,321 -19%
AI
45
Alphabet Inc
California
$246K – – –
Invesco
46
Invesco
Georgia
$246K +$38.1K +27,225 +18%
Barclays
47
Barclays
United Kingdom
$238K +$62.7K +44,709 +36%
MC
48
Medici Capital
California
$234K – – –
NL
49
Nuveen LLC
North Carolina
$218K +$24.4K +17,433 +13%
Los Angeles Capital Management
50
Los Angeles Capital Management
California
$213K +$10.6K +7,600 +5%
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