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Agios Pharmaceuticals

237 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 70 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $133M | Put options by funds: $45.6M

48% more first-time investments, than exits

New positions opened: 65 | Existing positions closed: 44

13% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 70

8% more funds holding

Funds holding: 220237 (+17)

4.24% less ownership

Funds ownership: 109.29%105.05% (-4.2%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$879M)

Holders
237
Holders Change
+17
Holders Change %
+7.73%
% of All Funds
2.88%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
65
Increased
79
Reduced
70
Closed
44
Calls
$133M
Puts
$45.6M
Net Calls
+$87.2M
Net Calls Change
+$80.1M
Name Holding Trade Value Shares
Change
Change in
Stake
EP
51
Edgestream Partners
New Jersey
$4.57M +$5.89M +167,998 New
Group One Trading
52
Group One Trading
Illinois
$4.54M +$5.85M +166,614 New
TAM
53
TFG Asset Management
Cayman Islands
$4.41M +$5.68M +162,018 New
American Century Companies
54
American Century Companies
Missouri
$4.12M +$223K +6,365 +4%
MCM
55
Moore Capital Management
New York
$4.08M +$3.33M +95,000 +173%
Allianz Asset Management
56
Allianz Asset Management
Germany
$4.03M +$45.9K +1,307 +0.9%
HS
57
HighVista Strategies
Massachusetts
$4.02M -$1.67M -47,636 -24%
HF
58
HRT Financial
New York
$3.99M +$5.14M +146,469 New
Invesco
59
Invesco
Georgia
$3.88M +$547K +15,604 +12%
EAM
60
Exome Asset Management
New York
$3.73M +$4.8M +136,942 New
UBS Group
61
UBS Group
Switzerland
$3.45M -$4.07M -116,148 -48%
Deutsche Bank
62
Deutsche Bank
Germany
$3.34M -$28.2M -803,859 -87%
Squarepoint
63
Squarepoint
New York
$3.31M +$4.27M +121,763 New
IC
64
Ikarian Capital
Texas
$3.14M -$403K -11,490 -9%
Jacobs Levy Equity Management
65
Jacobs Levy Equity Management
New Jersey
$3.03M +$3.9M +111,150 New
Assenagon Asset Management
66
Assenagon Asset Management
Luxembourg
$3.01M +$1.52M +43,287 +64%
Swiss National Bank
67
Swiss National Bank
Switzerland
$2.96M +$77.2K +2,200 +2%
Rafferty Asset Management
68
Rafferty Asset Management
New York
$2.93M +$1.38M +39,270 +58%
UBS AM
69
UBS AM
Illinois
$2.91M +$4.25K +121 +0.1%
Hudson Bay Capital Management
70
Hudson Bay Capital Management
Connecticut
$2.72M -$789K -22,500 -18%
PHP
71
Parkman Healthcare Partners
Connecticut
$2.71M -$27.2K -776 -0.8%
CM
72
Caption Management
Oklahoma
$2.54M +$2.67M +75,992 +434%
Citigroup
73
Citigroup
New York
$2.4M +$1.57M +44,618 +102%
Two Sigma Advisers
74
Two Sigma Advisers
New York
$2.32M +$2.51M +71,600 +526%
Prudential Financial
75
Prudential Financial
New Jersey
$2.21M -$603K -17,184 -17%