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Agios Pharmaceuticals
AGIO

Overview Fund Activity

213 hedge funds and large institutions have $2.05B invested in Agios Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 22 funds opening new positions, 87 increasing their positions, 76 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
213
Holders Change
-5
Holders Change %
-2.29%
% of All Funds
2.86%
Holding in Top 10
2
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-33.33%
% of All Funds
0.03%
New
22
Increased
87
Reduced
76
Closed
25
Calls
$11.2M
Puts
$8.65M
Net Calls
+$2.57M
Net Calls Change
+$3.05M

Top Buyers

1
PBA
Paradigm Biocapital Advisors
New York
$38M
2
TCM
TCG Crossover Management
California
$23.2M
3
RSCM
Rock Springs Capital Management
Maryland
$32.9M
4
Wellington Management Group
Wellington Management Group
Massachusetts
$14M
5
CP
Caligan Partners
New York
$35.6M

Top Sellers

1
PCH
Polar Capital Holdings
United Kingdom
$0
2
AC
Armistice Capital
New York
$38.8M
3
State Street
State Street
Massachusetts
$64.9M
4
BlackRock
BlackRock
New York
$161M
5
ACH
ArrowMark Colorado Holdings
Colorado
$21.9M
Name Holding Trade Value Shares
Change 		Shares
Change %
FCM
1
Farallon Capital Management
California
$192M +$2.23M +67,000 +1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$189M +$2.58M +77,428 +1%
BlackRock
3
BlackRock
New York
$161M -$9.15M -274,986 -5%
BG
4
Bellevue Group
Switzerland
$119M +$2.49M +75,000 +2%
EAM
5
Erste Asset Management
Austria
$77.4M +$3.21M +96,589 +4%
CC
6
Commodore Capital
New York
$77.3M +$4.66M +140,000 +6%
T. Rowe Price Associates
7
T. Rowe Price Associates
Maryland
$75.6M -$901K -27,104 -1%
State Street
8
State Street
Massachusetts
$64.9M -$16.6M -498,366 -20%
Macquarie Group
9
Macquarie Group
Australia
$63.2M +$1.66M +50,052 +3%
Geode Capital Management
10
Geode Capital Management
Massachusetts
$46.8M +$372K +11,174 +0.8%
FLSM
11
Frazier Life Sciences Management
California
$42.6M +$6.98M +209,900 +20%
AC
12
Armistice Capital
New York
$38.8M -$29.3M -880,000 -43%
PBA
13
Paradigm Biocapital Advisors
New York
$38M +$38M +1,142,511 New
Bank of America
14
Bank of America
North Carolina
$37.3M -$508K -15,284 -1%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$36.8M -$5.19M -155,980 -12%
Citadel Advisors
16
Citadel Advisors
Florida
$36M +$7.25M +217,971 +25%
CP
17
Caligan Partners
New York
$35.6M +$12.3M +369,978 +53%
JPMorgan Chase & Co
18
JPMorgan Chase & Co
New York
$34.2M -$730K -21,943 -2%
BNP Paribas Asset Management
19
BNP Paribas Asset Management
France
$33.8M -$294K -8,828 -0.9%
RSCM
20
Rock Springs Capital Management
Maryland
$32.9M +$21.5M +647,565 +189%
Deutsche Bank
21
Deutsche Bank
Germany
$30.7M -$246K -7,384 -0.8%
Fisher Asset Management
22
Fisher Asset Management
Washington
$29.2M -$2.72M -81,799 -9%
GKIM
23
GW&K Investment Management
Massachusetts
$28.9M +$1.7M +51,092 +6%
Adage Capital Partners
24
Adage Capital Partners
Massachusetts
$26.3M +$1.6M +48,000 +6%
TCM
25
TCG Crossover Management
California
$23.2M +$23.2M +697,003 New
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