Two Sigma Advisers’s Agios Pharmaceuticals AGIO Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-85,200	Closed	-$2.32M	–	58
2025 Q4	$2.32M	Buy	85,200 +71,600	+526%	+$2.51M	﹤0.01%	1122
2025 Q3	$546K	Buy	+13,600	New	+$512K	﹤0.01%	1730
2025 Q1	–	Sell	-22,200	Closed	-$729K	–	2368
2024 Q4	$729K	Buy	+22,200	New	+$1.04M	﹤0.01%	1613
2024 Q2	–	Sell	-20,900	Closed	-$611K	–	2422
2024 Q1	$611K	Buy	+20,900	New	+$560K	﹤0.01%	1786
2022 Q1	–	Sell	-6,400	Closed	-$210K	–	2719
2021 Q4	$210K	Buy	+6,400	New	+$258K	﹤0.01%	2275
2021 Q2	–	Sell	-16,500	Closed	-$852K	–	2430
2021 Q1	$852K	Buy	+16,500	New	+$817K	﹤0.01%	1737
2020 Q4	–	Sell	-38,200	Closed	-$1.34M	–	2366
2020 Q3	$1.34M	Buy	+38,200	New	+$1.67M	﹤0.01%	1369
2020 Q1	–	Sell	-35,100	Closed	-$1.68M	–	2445
2019 Q4	$1.68M	Buy	+35,100	New	+$1.33M	﹤0.01%	1313
2019 Q3	–	Sell	-5,400	Closed	-$269K	–	2207
2019 Q2	$269K	Buy	+5,400	New	+$289K	﹤0.01%	2048
2019 Q1	–	Sell	-34,200	Closed	-$1.58M	–	2284
2018 Q4	$1.58M	Buy	34,200 +7,300	+27%	+$451K	﹤0.01%	1292
2018 Q3	$2.08M	Sell	26,900 -43,500	-62%	-$3.5M	0.01%	1214
2018 Q2	$5.93M	Sell	70,400 -21,900	-24%	-$1.91M	0.02%	783
2018 Q1	$7.55M	Sell	92,300 -14,500	-14%	-$1.12M	0.02%	693
2017 Q4	$6.11M	Buy	106,800 +64,200	+151%	+$4.04M	0.02%	782
2017 Q3	$2.84M	Buy	42,600 +200	+0.5%	+$12K	0.01%	1042
2017 Q2	$2.18M	Buy	42,400 +5,200	+14%	+$266K	0.01%	1158
2017 Q1	$2.17M	Buy	37,200 +4,900	+15%	+$235K	0.01%	1214
2016 Q4	$1.35M	Buy	32,300 +18,300	+131%	+$960K	0.01%	1392
2016 Q3	$739K	Buy	+14,000	New	+$610K	﹤0.01%	1493