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Agios Pharmaceuticals

237 hedge funds and large institutions have $1.67B invested in Agios Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 65 funds opening new positions, 79 increasing their positions, 70 reducing their positions, and 44 closing their positions.

New
Increased
Maintained
Reduced
Closed

191% more call options, than puts

Call options by funds: $133M | Put options by funds: $45.6M

48% more first-time investments, than exits

New positions opened: 65 | Existing positions closed: 44

13% more repeat investments, than reductions

Existing positions increased: 79 | Existing positions reduced: 70

8% more funds holding

Funds holding: 220237 (+17)

4.24% less ownership

Funds ownership: 109.29%105.05% (-4.2%)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

35% less capital invested

Capital invested by funds: $2.55B → $1.67B (-$879M)

Holders
237
Holders Change
+17
Holders Change %
+7.73%
% of All Funds
2.88%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
65
Increased
79
Reduced
70
Closed
44
Calls
$133M
Puts
$45.6M
Net Calls
+$87.2M
Net Calls Change
+$80.1M
Name Holding Trade Value Shares
Change
Change in
Stake
SPIA
226
Steward Partners Investment Advisory
New York
$245
IA
227
IFP Advisors
Florida
$163
EP
228
Essential Partners
California
$136 -$3.86K -110 -96%
RIL
229
Rothschild Investment LLC
Illinois
$136 -$2.46K -70 -93%
FFO
230
Fortitude Family Office
Arizona
$136
JWA
231
JFS Wealth Advisors
Pennsylvania
$109 -$421 -12 -75%
SS
232
SBI Securities
Japan
$109
BHWM
233
Bay Harbor Wealth Management
Maryland
$108 +$35 +1 +33%
RWM
234
Rialto Wealth Management
New York
$55
DF
235
Dunhill Financial
United Kingdom
$50 +$70 +2 New
SIC
236
SJS Investment Consulting
Ohio
$28 -$35 -1 -50%
Jones Financial Companies
237
Jones Financial Companies
Missouri
$27
BG
238
Bellevue Group
Switzerland
-$149M -3,714,736 Closed
PBA
239
Paradigm Biocapital Advisors
New York
-$107M -2,673,555 Closed
CC
240
Commodore Capital
New York
-$93.9M -2,338,287 Closed
Macquarie Group
241
Macquarie Group
Australia
-$78.6M -1,958,101 Closed
CP
242
Caligan Partners
New York
-$39.7M -1,131,205 Closed
Fisher Asset Management
243
Fisher Asset Management
Washington
-$34.9M -870,145 Closed
Adage Capital Partners
244
Adage Capital Partners
Massachusetts
-$32.1M -800,000 Closed
SC
245
SummitTX Capital
Texas
-$10.6M -262,977 Closed
EHI
246
Eagle Health Investments
Connecticut
-$9.88M -246,230 Closed
BBA
247
Baker Bros. Advisors
New York
-$7.62M -189,866 Closed
PCM
248
Peregrine Capital Management
Minnesota
-$6.54M -162,905 Closed
Alyeska Investment Group
249
Alyeska Investment Group
Illinois
-$5.88M -146,514 Closed
PSC
250
Patient Square Capital
California
-$5.37M -133,827 Closed