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AC Immune
ACIU

40 hedge funds and large institutions have $71.1M invested in AC Immune in 2025 Q3 according to their latest regulatory filings, with 4 funds opening new positions, 14 increasing their positions, 12 reducing their positions, and 6 closing their positions.

New
Increased
Maintained
Reduced
Closed

237% more call options, than puts

Call options by funds: $293K | Put options by funds: $87K

43% more capital invested

Capital invested by funds: $49.7M → $71.1M (+$21.4M)

17% more repeat investments, than reductions

Existing positions increased: 14 | Existing positions reduced: 12

0.12% more ownership

Funds ownership: 24.4% → 24.52% (+0.12%)

5% less funds holding

Funds holding: 42 → 40 (-2)

33% less first-time investments, than exits

New positions opened: 4 | Existing positions closed: 6

Holders
40
Holders Change
-2
Holders Change %
-4.76%
% of All Funds
0.52%
Holding in Top 10
–
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
–
New
4
Increased
14
Reduced
12
Closed
6
Calls
$293K
Puts
$87K
Net Calls
+$206K
Net Calls Change
+$298K

Top Buyers

Rank Fund Capital Flow
1
Millennium Management
Millennium Management
New York
+$1.36M
2
Assenagon Asset Management
Assenagon Asset Management
Luxembourg
+$429K
3
Susquehanna International Group
Susquehanna International Group
Pennsylvania
+$49.3K
4
Morgan Stanley
Morgan Stanley
New York
+$43.2K
5
PAG
Private Advisor Group
New Jersey
+$37.5K

Top Sellers

Rank Fund Capital Flow
1
Citadel Advisors
Citadel Advisors
Florida
-$284K
2
Marshall Wace
Marshall Wace
United Kingdom
-$276K
3
Northern Trust
Northern Trust
Illinois
-$224K
4
Handelsbanken Fonder
Handelsbanken Fonder
Sweden
-$213K
5
EP
Eversept Partners
New York
-$205K
Name Holding Trade Value Shares
Change 		Change in
Stake
Bank of America
26
Bank of America
North Carolina
$17.1K +$775 +343 +6%
Barclays
27
Barclays
United Kingdom
$15.3K -$5.91K -2,617 -33%
State of Tennessee, Department of Treasury
28
State of Tennessee, Department of Treasury
Tennessee
$14.8K – – –
Mirae Asset Global Investments
29
Mirae Asset Global Investments
South Korea
$11.2K +$7 +3 +0.1%
TRCT
30
Tower Research Capital (TRC)
New York
$9.55K +$522 +231 +8%
Simplex Trading
31
Simplex Trading
Illinois
$9K +$6.64K +2,940 +925%
BNP Paribas Financial Markets
32
BNP Paribas Financial Markets
France
$8.1K +$3.33K +1,476 +111%
GFM
33
GF Fund Management
China
$6.24K -$664 -294 -12%
Citigroup
34
Citigroup
New York
$5.58K +$36 +16 +0.8%
Royal Bank of Canada
35
Royal Bank of Canada
Ontario, Canada
$5K +$497 +220 +14%
AWM
36
Activest Wealth Management
Florida
$2.89K – – –
Rockefeller Capital Management
37
Rockefeller Capital Management
New York
$2.89K +$2.26K +1,000 New
SS
38
SBI Securities
Japan
$1.58K -$38 -17 -3%
Osaic Holdings
39
Osaic Holdings
Arizona
$724 – – –
SFCL
40
Strengthening Families & Communities LLC
Massachusetts
$578 – – –
Marshall Wace
41
Marshall Wace
United Kingdom
– -$276K -135,841 Closed
Handelsbanken Fonder
42
Handelsbanken Fonder
Sweden
– -$213K -105,000 Closed
EP
43
Eversept Partners
New York
– -$205K -100,752 Closed
CF
44
Cantor Fitzgerald
New York
– -$60.9K -30,000 Closed
Squarepoint
45
Squarepoint
New York
– -$25.7K -12,642 Closed
TSS
46
Two Sigma Securities
New York
– -$20.5K -10,085 Closed
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ACIU Hedge Fund Activity: Q3 2025 in Review

40 of the 7,631 institutional investors tracked by Wall St. Rank reported a position in AC Immune (ACIU) for Q3 2025, worth a combined $71.1M — up 43% from $49.7M a quarter earlier.

Sellers outnumbered buyers: 6 funds closed out of ACIU and 4 opened new positions — a net loss of 2 holders — while 12 trimmed existing stakes and 14 added.

The largest buyer was Millennium Management, adding an estimated $1.36M. The largest seller was Citadel Advisors, cutting an estimated $284K.

  • 40 institutional investors held AC Immune (ACIU) as of Q3 2025, down from 42 in Q2 2025.
  • Funds reported $71.1M of AC Immune stock for Q3 2025, up 43% quarter-over-quarter.
  • 4 funds opened new AC Immune positions in Q3 2025 and 6 closed out, a net change of -2 holders.
  • The largest AC Immune buyer in Q3 2025 was Millennium Management, an estimated $1.36M added.
  • The largest AC Immune seller in Q3 2025 was Citadel Advisors, an estimated $284K sold.

Based on aggregated 13F filings for Q3 2025.