|
1
|
Baker Bros. Advisors
New York
|
$1.34B
|
–
|
–
|
–
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$419M
|
-$5.27M
|
-220,731
|
-2%
|
|
|
3
|
|
$357M
|
+$33M
|
+1,381,898
|
+14%
|
|
|
4
|
|
$352M
|
-$7.71M
|
-322,986
|
-3%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$202M
|
+$29.9M
|
+1,251,295
|
+24%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$188M
|
–
|
–
|
–
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$165M
|
-$875K
|
-36,622
|
-0.7%
|
|
|
8
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$162M
|
-$1.23M
|
-51,652
|
-1%
|
|
|
9
|
|
$118M
|
-$24.7M
|
-1,034,400
|
-22%
|
|
|
10
|
Fred Alger Management
New York
|
$99.5M
|
+$1.62M
|
+67,892
|
+2%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$84.3M
|
+$2.72M
|
+113,770
|
+4%
|
|
|
12
|
Palo Alto Investors
Palo Alto,
California
|
$75.4M
|
+$89.9K
|
+3,763
|
+0.2%
|
|
|
13
|
First Trust Advisors
Wheaton,
Illinois
|
$55.6M
|
+$3.55M
|
+148,526
|
+9%
|
|
|
14
|
Millennium Management
New York
|
$55.3M
|
-$15.5M
|
-648,786
|
-27%
|
|
|
15
|
Emerald Advisers
Leola,
Pennsylvania
|
$51.5M
|
-$847K
|
-35,487
|
-2%
|
|
|
16
|
Pictet Asset Management
Carouge,
Switzerland
|
$45.8M
|
+$2.62M
|
+109,635
|
+8%
|
|
|
17
|
|
$45.2M
|
+$5.67M
|
+237,400
|
+20%
|
|
|
18
|
|
$42.6M
|
-$11.8M
|
-494,480
|
-27%
|
|
|
19
|
Jupiter Asset Management
London,
United Kingdom
|
$41.4M
|
+$1.1M
|
+46,148
|
+4%
|
|
|
20
|
Emerald Mutual Fund Advisers Trust
Leola,
Pennsylvania
|
$40.8M
|
+$13.6K
|
+568
|
+0%
|
|
|
21
|
Voloridge Investment Management
Jupiter,
Florida
|
$40.1M
|
+$5.68M
|
+237,676
|
+23%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$38M
|
-$156K
|
-6,544
|
-0.5%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$35.3M
|
+$1.31M
|
+54,814
|
+5%
|
|
|
24
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$32.1M
|
+$22.9M
|
+958,543
|
+1,433%
|
|
|
25
|
Manulife (Manufacturers Life Insurance)
Canada,
Ontario, Canada
|
$26.5M
|
-$4.88M
|
-204,366
|
-19%
|
|
