|
1
|
Baker Bros. Advisors
New York
|
$1.02B
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$327M
|
-$8.69M
|
-359,301
|
-3%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$305M
|
+$6.42M
|
+265,448
|
+2%
|
|
|
4
|
|
$241M
|
-$2.18M
|
-90,289
|
-0.9%
|
|
|
5
|
EcoR1 Capital
San Francisco,
California
|
$145M
|
+$70.9M
|
+2,930,886
|
+96%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$122M
|
+$5.74M
|
+237,241
|
+5%
|
|
|
7
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$121M
|
-$109M
|
-4,507,325
|
-48%
|
|
|
8
|
|
$110M
|
+$478K
|
+19,760
|
+0.4%
|
|
|
9
|
First Trust Advisors
Wheaton,
Illinois
|
$56.5M
|
-$24.7M
|
-1,020,729
|
-30%
|
|
|
10
|
|
$56M
|
+$2.62M
|
+108,179
|
+5%
|
|
|
11
|
Janus Henderson Group
London,
|
$55.6M
|
+$6.25M
|
+258,295
|
+13%
|
|
|
12
|
Avoro Capital Advisors
New York
|
$55.1M
|
+$1.81M
|
+75,000
|
+3%
|
|
|
13
|
Palo Alto Investors
Palo Alto,
California
|
$54.5M
|
-$2.08M
|
-86,043
|
-4%
|
|
|
14
|
Geode Capital Management
Boston,
Massachusetts
|
$53.3M
|
+$926K
|
+38,273
|
+2%
|
|
|
15
|
Fred Alger Management
New York
|
$41.6M
|
-$3M
|
-123,916
|
-7%
|
|
|
16
|
Boxer Capital
San Diego,
California
|
$30.6M
|
+$26.1M
|
+1,078,930
|
+583%
|
|
|
17
|
Artisan Partners
Milwaukee,
Wisconsin
|
$29.7M
|
-$4.06M
|
-167,868
|
-12%
|
|
|
18
|
|
$29.1M
|
+$3M
|
+124,000
|
+12%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$28.4M
|
-$1.31M
|
-54,096
|
-4%
|
|
|
20
|
Fairmount Funds Management
West Conshohocken,
Pennsylvania
|
$28M
|
+$17.9M
|
+740,000
|
+178%
|
|
|
21
|
|
$26.7M
|
-$1.88M
|
-77,546
|
-7%
|
|
|
22
|
Millennium Management
New York
|
$26.3M
|
+$11.7M
|
+483,876
|
+80%
|
|
|
23
|
Ameriprise
Minneapolis,
Minnesota
|
$26.1M
|
-$1.91M
|
-78,757
|
-7%
|
|
|
24
|
|
$22.8M
|
+$6.72M
|
+277,723
|
+42%
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$22.7M
|
+$1.3M
|
+53,773
|
+6%
|
|
