XTX Topco’s Orchestra BioMed OBIO Stock Holding History

XTX Topco’s Portfolio OBIO Stock Details OBIO Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	–	Sell	-50,358	Closed	-$209K	–	4208
2025 Q4	$209K	Buy	50,358 +15,540	+45%	+$62.7K	0.01%	2367
2025 Q3	$86.3K	Buy	34,818 +18,001	+107%	+$49.7K	﹤0.01%	2060
2025 Q2	$45.1K	Buy	+16,817	New	+$49.1K	﹤0.01%	2031

Other funds holding OBIO

RTW Investments New York $10B AUM 135.35% 1-Year Est. Return

Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

Alyeska Investment Group Chicago, Illinois $35.4B AUM 33.54% 1-Year Est. Return

PBM

Propel Bio Management Los Angeles, California $159M AUM 60.94% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

AAA

Affinity Asset Advisors New York $1.94B AUM 374.45% 1-Year Est. Return

Charles Schwab San Francisco, California $654B AUM 26.35% 1-Year Est. Return

XTX Topco's OBIO Position: Q1 2026 in Review

XTX Topco sold out of Orchestra BioMed (OBIO) in Q1 2026, closing a stake of 50,358 shares — an estimated $209K sold.

XTX Topco first reported a position in OBIO in Q2 2025 and held it in 3 quarters. The position peaked at $209K in Q4 2025. 65 funds tracked by Wall St. Rank hold OBIO as of Q1 2026.

XTX Topco reported no remaining Orchestra BioMed position as of Q1 2026 after selling out during the quarter.
XTX Topco sold 50,358 Orchestra BioMed shares in Q1 2026, an estimated $209K.
XTX Topco first reported a position in Orchestra BioMed in Q2 2025 and held it in 3 quarters.
XTX Topco's Orchestra BioMed position peaked at $209K in Q4 2025.
65 funds tracked by Wall St. Rank held Orchestra BioMed as of Q1 2026.

Based on XTX Topco's 13F filing for Q1 2026, filed 15 May 2026.