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William Blair Investment Management

William Blair Investment Management Portfolio holdings

AUM $30.3B
1-Year Est. Return 33.75%
This Fund
S&P 500
This Quarter Est. Return
+3.11%
1 Year Est. Return
+33.75%
3 Year Est. Return
+108.55%
5 Year Est. Return
+126.9%
10 Year Est. Return
+788.31%
AUM
$35.9B
AUM Growth
-$2.82B
Cap. Flow
-$3B
Cap. Flow %
-8.37%
Top 10 Hldgs %
32.55%
Holding
459
New
45
Increased
106
Reduced
259
Closed
46

Top Buys

Rank Stock Value
1
SNOW icon
Snowflake
SNOW
+$202M
2
ARGX icon
argenx
ARGX
+$191M
3
GOOGL icon
Alphabet (Google) Class A
GOOGL
+$191M
4
HQY icon
HealthEquity
HQY
+$178M
5
FFIV icon
F5
FFIV
+$148M

Top Sells

Rank Stock Value
1
LRCX icon
Lam Research
LRCX
+$270M
2
CIEN icon
Ciena
CIEN
+$260M
3
UBER icon
Uber
UBER
+$233M
4
LYV icon
Live Nation Entertainment
LYV
+$229M
5
LRN icon
Stride
LRN
+$225M

Sector Composition

Rank Sector Weight
1 Technology 37.93%
2 Financials 12.94%
3 Healthcare 12.67%
4 Consumer Discretionary 10.8%
5 Industrials 9.43%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
ITUB icon
26
Itaú Unibanco
ITUB
$82.7B
$262M 0.73%
36,551,763
+6,197,462
+20% +$44.1M
CIEN icon
27
Ciena
CIEN
$54.9B
$257M 0.72%
1,098,593
-1,342,295
-55% -$260M
UNH icon
28
UnitedHealth
UNH
$361B
$252M 0.7%
762,243
-6,292
-0.8% -$2.13M
P
29
Everpure Inc
P
$36.4B
$251M 0.7%
3,742,928
-923,964
-20% -$77.2M
ORCL icon
30
Oracle
ORCL
$419B
$245M 0.68%
1,256,536
+148,950
+13% +$35.5M
DOCS icon
31
Doximity
DOCS
$4.65B
$242M 0.67%
5,456,985
-372,184
-6% -$20.9M
TYL icon
32
Tyler Technologies
TYL
$13.2B
$225M 0.63%
495,297
+36,183
+8% +$17.2M
BAP icon
33
Credicorp
BAP
$30B
$220M 0.61%
767,413
-52,660
-6% -$13.9M
GMED icon
34
Globus Medical
GMED
$11.4B
$220M 0.61%
2,519,782
-299,383
-11% -$22.7M
TLN
35
Talen Energy Corp
TLN
$17.1B
$213M 0.6%
569,399
-110,298
-16% -$42.9M
INSM icon
36
Insmed
INSM
$29B
$213M 0.59%
1,221,096
-333,961
-21% -$60.9M
PRMB
37
Primo Brands
PRMB
$8.55B
$206M 0.58%
12,627,420
+793,036
+7% +$14.7M
MDGL icon
38
Madrigal Pharmaceuticals
MDGL
$12.4B
$206M 0.58%
354,220
-57,582
-14% -$29.4M
MLI icon
39
Mueller Industries
MLI
$15.1B
$204M 0.57%
3,559,812
-429,938
-11% -$23.1M
EG icon
40
Everest Group
EG
$14B
$198M 0.55%
584,301
-67,173
-10% -$22.2M
VEEV icon
41
Veeva Systems
VEEV
$38.4B
$197M 0.55%
881,223
+132,579
+18% +$35.2M
QTWO icon
42
Q2 Holdings
QTWO
$3.95B
$194M 0.54%
2,694,718
+553,713
+26% +$38M
BWXT icon
43
BWX Technologies
BWXT
$15.5B
$191M 0.53%
1,107,600
-147,710
-12% -$27.7M
TWST icon
44
Twist Bioscience
TWST
$7.72B
$189M 0.53%
5,954,429
+1,812,146
+44% +$56.5M
ARGX icon
45
argenx
ARGX
$54.1B
$188M 0.52%
+223,666
New +$191M
BWIN
46
Baldwin Insurance Group
BWIN
$2.88B
$181M 0.51%
7,543,813
+2,439,118
+48% +$62.1M
CCJ icon
47
Cameco
CCJ
$43B
$181M 0.51%
1,980,827
-657,206
-25% -$59.2M
BCO icon
48
Brink's
BCO
$4.69B
$180M 0.5%
1,544,641
-225,226
-13% -$25.8M
CPRT icon
49
Copart
CPRT
$27.2B
$180M 0.5%
4,585,833
-65,641
-1% -$2.72M
WAY
50
Waystar Holding Corp
WAY
$4.66B
$173M 0.48%
5,282,220
+19,033
+0.4% +$678K

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William Blair Investment Management's Q4 2025 Portfolio in Review

As of Q4 2025, William Blair Investment Management held 459 positions worth $35.9B, down 7.3% from $38.7B the previous quarter. Its ten largest holdings account for 33% of the portfolio.

William Blair Investment Management withdrew a net $3B in Q4 2025, closing 46 positions and reducing 259 holdings. Its most notable exit was Live Nation Entertainment, an estimated $229M position sold in full.

By sector, the portfolio is most concentrated in Technology at 38% of assets, down from 39% a quarter earlier, followed by Financials and Healthcare.

Against the trend, William Blair Investment Management opened a new position in argenx worth $188M.

  • William Blair Investment Management's largest Q4 2025 buy was argenx: 223,666 shares worth $188M.
  • William Blair Investment Management added most to Snowflake in Q4 2025, an estimated $202M increase.
  • William Blair Investment Management's biggest Q4 2025 reduction was Lam Research, cutting an estimated $270M.
  • William Blair Investment Management fully exited Live Nation Entertainment in Q4 2025, selling an estimated $229M.
  • William Blair Investment Management's ten largest holdings make up 33% of its $35.9B portfolio in Q4 2025.
  • William Blair Investment Management opened 45 new positions and closed 46 in Q4 2025.
  • William Blair Investment Management's portfolio value fell 7.3% quarter-over-quarter to $35.9B.

Based on William Blair Investment Management's 13F filing for Q4 2025, filed 9 Feb 2026.