William Blair Investment Management Portfolio holdings
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Snowflake
SNOW
|
+$202M |
| 2 |
argenx
ARGX
|
+$191M |
| 3 |
Alphabet (Google) Class A
GOOGL
|
+$191M |
| 4 |
HealthEquity
HQY
|
+$178M |
| 5 |
F5
FFIV
|
+$148M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Lam Research
LRCX
|
+$270M |
| 2 |
Ciena
CIEN
|
+$260M |
| 3 |
Uber
UBER
|
+$233M |
| 4 |
Live Nation Entertainment
LYV
|
+$229M |
| 5 |
Stride
LRN
|
+$225M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 37.93% |
| 2 | Financials | 12.94% |
| 3 | Healthcare | 12.67% |
| 4 | Consumer Discretionary | 10.8% |
| 5 | Industrials | 9.43% |
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William Blair Investment Management's Q4 2025 Portfolio in Review
As of Q4 2025, William Blair Investment Management held 459 positions worth $35.9B, down 7.3% from $38.7B the previous quarter. Its ten largest holdings account for 33% of the portfolio.
William Blair Investment Management withdrew a net $3B in Q4 2025, closing 46 positions and reducing 259 holdings. Its most notable exit was Live Nation Entertainment, an estimated $229M position sold in full.
By sector, the portfolio is most concentrated in Technology at 38% of assets, down from 39% a quarter earlier, followed by Financials and Healthcare.
Against the trend, William Blair Investment Management opened a new position in argenx worth $188M.
- William Blair Investment Management's largest Q4 2025 buy was argenx: 223,666 shares worth $188M.
- William Blair Investment Management added most to Snowflake in Q4 2025, an estimated $202M increase.
- William Blair Investment Management's biggest Q4 2025 reduction was Lam Research, cutting an estimated $270M.
- William Blair Investment Management fully exited Live Nation Entertainment in Q4 2025, selling an estimated $229M.
- William Blair Investment Management's ten largest holdings make up 33% of its $35.9B portfolio in Q4 2025.
- William Blair Investment Management opened 45 new positions and closed 46 in Q4 2025.
- William Blair Investment Management's portfolio value fell 7.3% quarter-over-quarter to $35.9B.
Based on William Blair Investment Management's 13F filing for Q4 2025, filed 9 Feb 2026.