Vanguard Group
SION

Vanguard Group’s Sionna Therapeutics SION Stock Holding History

Vanguard Group’s Portfolio SION Stock Details SION Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		$48.7M Buy
1,184,951
+41,797
+4% +$1.58M ﹤0.01% 2172
2025
Q3 		$33.6M Buy
1,143,154
+512,803
+81% +$11.2M ﹤0.01% 2360
2025
Q2 		$10.9M Buy
630,351
+84,184
+15% +$1.1M ﹤0.01% 2861
2025
Q1 		$5.71M Buy
+546,167
New +$8.92M ﹤0.01% 3116

Other funds holding SION

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGA
TPG GP A Fort Worth, Texas $3.68B AUM 14.99% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.7B AUM 21.3% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Jennison Associates
Jennison Associates New York $145B AUM 34.61% 1-Year Est. Return

Vanguard Group's SION Position: Q4 2025 in Review

Vanguard Group increased its Sionna Therapeutics (SION) stake by 3.7% in Q4 2025, buying an estimated $1.58M and bringing the position to 1,184,951 shares worth $48.7M. The position accounts for ﹤0.01% of the portfolio, ranked #2172.

Vanguard Group first reported a position in SION in Q1 2025 and has held it in 4 quarters since. 101 funds tracked by Wall St. Rank hold SION as of Q4 2025.

  • Vanguard Group held 1,184,951 shares of Sionna Therapeutics worth $48.7M as of Q4 2025.
  • Vanguard Group bought 41,797 Sionna Therapeutics shares in Q4 2025, an estimated $1.58M.
  • Sionna Therapeutics made up ﹤0.01% of Vanguard Group's portfolio in Q4 2025, its #2172 holding.
  • Vanguard Group first reported a position in Sionna Therapeutics in Q1 2025 and has held it in 4 quarters since.
  • 101 funds tracked by Wall St. Rank held Sionna Therapeutics as of Q4 2025.

Based on Vanguard Group's 13F filing for Q4 2025, filed 29 Jan 2026.