TSS
ITRM

Two Sigma Securities’s Iterum Therapeutics ITRM Stock Holding History

Two Sigma Securities’s Portfolio ITRM Stock Details ITRM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q2 		– Sell
-10,709
Closed -$13.2K – 1786
2025
Q1 		$13.2K Buy
+10,709
New +$15.9K ﹤0.01% 1177
2024
Q4 		– Sell
-14,947
Closed -$16.3K – 2406
2024
Q3 		$16.3K Buy
+14,947
New +$17.8K ﹤0.01% 2530
2022
Q1 		– Sell
-5,511
Closed -$32K – 2306
2021
Q4 		$32K Buy
+5,511
New +$42.6K ﹤0.01% 1345
2021
Q2 		– Sell
-2,341
Closed -$50K – 1594
2021
Q1 		$50K Buy
+2,341
New +$55.7K ﹤0.01% 733

Other funds holding ITRM

Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
Squarepoint
Squarepoint New York $90.5B AUM 33.95% 1-Year Est. Return
SM
Sabby Management Miami Beach, Florida $111M AUM 74.4% 1-Year Est. Return
NLVP
New Leaf Venture Partners New York $43M AUM 25.55% 1-Year Est. Return
AF
Apollon Financial Mount Pleasant, South Carolina $848M AUM 27.31% 1-Year Est. Return
OIA
OneDigital Investment Advisors Overland Park, Kansas $11.8B AUM 21.23% 1-Year Est. Return
Jane Street
Jane Street New York $1.21T AUM 78.12% 1-Year Est. Return
CFD
Creative Financial Designs Kokomo, Indiana $2.1B AUM 23.1% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return
SA
Sanctuary Advisors Indianapolis, Indiana $21.6B AUM 28.31% 1-Year Est. Return

Two Sigma Securities's ITRM Position: Q2 2025 in Review

Two Sigma Securities sold out of Iterum Therapeutics (ITRM) in Q2 2025, closing a stake of 10,709 shares — an estimated $13.2K sold.

Two Sigma Securities first reported a position in ITRM in Q1 2021 and held it in 4 quarters. The position peaked at $50K in Q1 2021. 24 funds tracked by Wall St. Rank hold ITRM as of Q2 2025.

  • Two Sigma Securities reported no remaining Iterum Therapeutics position as of Q2 2025 after selling out during the quarter.
  • Two Sigma Securities sold 10,709 Iterum Therapeutics shares in Q2 2025, an estimated $13.2K.
  • Two Sigma Securities first reported a position in Iterum Therapeutics in Q1 2021 and held it in 4 quarters.
  • Two Sigma Securities's Iterum Therapeutics position peaked at $50K in Q1 2021.
  • 24 funds tracked by Wall St. Rank held Iterum Therapeutics as of Q2 2025.

Based on Two Sigma Securities's 13F filing for Q2 2025, filed 14 Aug 2025.