Two Sigma Investments
ITRM

Two Sigma Investments’s Iterum Therapeutics ITRM Stock Holding History

Two Sigma Investments’s Portfolio ITRM Stock Details ITRM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-25,245
Closed -$25.1K – 3790
2025
Q2 		$25.1K Hold
25,245
– – ﹤0.01% 3104
2025
Q1 		$31.1K Hold
25,245
– – ﹤0.01% 3079
2024
Q4 		$44.7K Buy
+25,245
New +$39.6K ﹤0.01% 3056
2021
Q3 		– Sell
-35,237
Closed -$1.22M – 4461
2021
Q2 		$1.22M Buy
35,237
+6,545
+23% +$142K ﹤0.01% 2307
2021
Q1 		$607K Buy
+28,692
New +$683K ﹤0.01% 2747
2020
Q4 		– Sell
-4,876
Closed -$77K – 3537
2020
Q3 		$77K Buy
4,876
+663
+16% +$8.86K ﹤0.01% 2960
2020
Q2 		$75K Buy
+4,213
New +$167K ﹤0.01% 2817

Other funds holding ITRM

Squarepoint
Squarepoint New York $90.5B AUM 33.95% 1-Year Est. Return
AF
Apollon Financial Mount Pleasant, South Carolina $848M AUM 27.31% 1-Year Est. Return
OIA
OneDigital Investment Advisors Overland Park, Kansas $11.8B AUM 21.23% 1-Year Est. Return
CAPTRUST Financial Advisors
CAPTRUST Financial Advisors Raleigh, North Carolina $65.5B AUM 24.25% 1-Year Est. Return
GWP
Gen-Wealth Partners Zeeland, Michigan $360M AUM 27.44% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $72.6B AUM 54.88% 1-Year Est. Return
VF
Virtu Financial New York $3.18B AUM 65.92% 1-Year Est. Return
KF
Krilogy Financial St. Louis, Missouri $3.38B AUM 30.57% 1-Year Est. Return
SA
Sanctuary Advisors Indianapolis, Indiana $21.6B AUM 28.31% 1-Year Est. Return
SG Americas Securities
SG Americas Securities New York $179B AUM 65.34% 1-Year Est. Return

Two Sigma Investments's ITRM Position: Q3 2025 in Review

Two Sigma Investments sold out of Iterum Therapeutics (ITRM) in Q3 2025, closing a stake of 25,245 shares — an estimated $25.1K sold.

Two Sigma Investments first reported a position in ITRM in Q2 2020 and held it in 7 quarters. The position peaked at $1.22M in Q2 2021. 24 funds tracked by Wall St. Rank hold ITRM as of Q3 2025.

  • Two Sigma Investments reported no remaining Iterum Therapeutics position as of Q3 2025 after selling out during the quarter.
  • Two Sigma Investments sold 25,245 Iterum Therapeutics shares in Q3 2025, an estimated $25.1K.
  • Two Sigma Investments first reported a position in Iterum Therapeutics in Q2 2020 and held it in 7 quarters.
  • Two Sigma Investments's Iterum Therapeutics position peaked at $1.22M in Q2 2021.
  • 24 funds tracked by Wall St. Rank held Iterum Therapeutics as of Q3 2025.

Based on Two Sigma Investments's 13F filing for Q3 2025, filed 14 Nov 2025.