Two Sigma Securities’s Ensysce Biosciences ENSC Stock Holding History

Two Sigma Securities’s Portfolio ENSC Stock Details ENSC Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$3.76K	Buy	+12,953	New	+$4.68K	﹤0.01%	1604
2026 Q1	–	Sell	-21,605	Closed	-$19.9K	–	1785
2025 Q4	$19.9K	Buy	+21,605	New	+$40.1K	﹤0.01%	1183
2023 Q4	–	Sell	-974	Closed	-$20.2K	–	3165
2023 Q3	$20.2K	Buy	+974	New	+$27.6K	﹤0.01%	2569
2022 Q4	–	Sell	-9	Closed	-$7K	–	2749
2022 Q3	$7K	Buy	9 +2	+29%	+$3.26K	﹤0.01%	2443
2022 Q2	$21K	Buy	+7	New	+$19.6K	﹤0.01%	1952
2021 Q4	–	Sell	-3	Closed	-$34K	–	1668
2021 Q3	$34K	Buy	+3	New	+$58.6K	﹤0.01%	1419

Other funds holding ENSC

Jane Street New York $1.21T AUM 78.12% 1-Year Est. Return

Adage Capital Partners Boston, Massachusetts $71.3B AUM 56.8% 1-Year Est. Return

Virtu Financial New York $3.18B AUM 65.92% 1-Year Est. Return

Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return

Citadel Advisors Miami, Florida $875B AUM 40.89% 1-Year Est. Return

XTX Topco George Town, Cayman Islands $7.72B AUM 32.88% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

HRT Financial New York $54.8B AUM 81.03% 1-Year Est. Return

Susquehanna International Group Bala Cynwyd, Pennsylvania $1.28T AUM 58.89% 1-Year Est. Return

TIAM2

Tru Independence Asset Management 2 Portland, Oregon $185M AUM 20.3% 1-Year Est. Return

Two Sigma Securities's ENSC Position: Q2 2026 in Review

Two Sigma Securities opened a new position in Ensysce Biosciences (ENSC) in Q2 2026: 12,953 shares worth $3.76K. The stake represents ﹤0.01% of the portfolio and ranks #1604 among its holdings. This is a return to the name: Two Sigma Securities previously reported a position in ENSC as recently as Q4 2025.

Two Sigma Securities first reported a position in ENSC in Q3 2021 and has held it in 6 quarters since. The position peaked at $34K in Q3 2021. 18 funds tracked by Wall St. Rank hold ENSC as of Q2 2026.

Two Sigma Securities held 12,953 shares of Ensysce Biosciences worth $3.76K as of Q2 2026.
Ensysce Biosciences was a new Two Sigma Securities position in Q2 2026.
Ensysce Biosciences made up ﹤0.01% of Two Sigma Securities's portfolio in Q2 2026, its #1604 holding.
Two Sigma Securities first reported a position in Ensysce Biosciences in Q3 2021 and has held it in 6 quarters since.
Two Sigma Securities's Ensysce Biosciences position peaked at $34K in Q3 2021.
18 funds tracked by Wall St. Rank held Ensysce Biosciences as of Q2 2026.

Based on Two Sigma Securities's 13F filing for Q2 2026, filed 14 Aug 2026.